Wilson R P, Lloyd J
Ophthalmic Surg. 1986 Jan;17(1):30-3.
The advantages of sodium hyaluronate (Healon) in filtering surgery have been mostly theoretical, with no study of sufficient numbers to justify its use. The authors used sodium hyaluronate in 119 consecutive trabeculectomies. These were compared to a control group of 122 cases. The long-term intraocular pressure and visual acuity results between the two groups were indistinguishable. The only definite benefit noted with the use of sodium hyaluronate was the lower incidence of hyphemas. No side-effects were seen. Its ability to maintain a deep anterior chamber and encourage hemostasis makes sodium hyaluronate useful in teaching goniotomies as well as performing trabeculectomies in congenital glaucoma. Sodium hyaluronate can also be used to evacuate hyphemas and dissect adhesions with minimal trauma, and may be healthier for the corneal endothelium than air in anterior chamber reformations.
透明质酸钠(Healon)在滤过性手术中的优势大多只是理论上的,尚无足够数量的研究来证明其使用的合理性。作者在连续119例小梁切除术中使用了透明质酸钠。将这些病例与122例对照组进行比较。两组之间的长期眼压和视力结果没有差异。使用透明质酸钠唯一明确的益处是前房积血的发生率较低。未观察到副作用。透明质酸钠维持前房深度和促进止血的能力使其在先天性青光眼的房角切开术教学以及小梁切除术操作中有用。透明质酸钠还可用于在前房积血清除和粘连分离中造成最小创伤,并且在前房重建中对角膜内皮可能比空气更有益。