Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, 450075 Ufa, Russia.
Department of Materials Science and Physics of Metals, Ufa University of Science and Technology, 450008 Ufa, Russia.
Int J Mol Sci. 2024 Oct 29;25(21):11623. doi: 10.3390/ijms252111623.
The general trend of increasing life expectancy will consistently drive the demand for orthopedic prostheses. In addition to the elderly, the younger population is also in urgent need of orthopedic devices, as bone fractures are a relatively common injury type; it is important to treat the patient quickly, painlessly, and eliminate further health complications. In the field of traumatology and orthopedics, metals and their alloys are currently the most commonly used materials. In this context, numerous scientists are engaged in the search for new implant materials and coatings. Among the various coating techniques, plasma electrolytic oxidation (PEO) (or micro-arc oxidation-MAO) occupy a distinct position. This method offers a cost-effective and environmentally friendly approach to modification of metal surfaces. PEO can effectively form porous, corrosion-resistant, and bioactive coatings on light alloys. The porous oxide surface structure welcomes organic molecules that can significantly enhance the corrosion resistance of the implant and improve the biological response of the body. The review considers the most crucial aspects of new combined PEO-organic coatings on metal implants, in terms of their potential for implantation, corrosion resistance, and biological activity in vitro and in vivo.
预期寿命的普遍增长趋势将持续推动对骨科假体的需求。除了老年人，年轻人群也急需骨科器械，因为骨折是一种相对常见的损伤类型；快速、无痛地治疗患者并消除进一步的健康并发症非常重要。在创伤学和骨科领域，金属及其合金目前是最常用的材料。在这种情况下，许多科学家都在寻找新的植入材料和涂层。在各种涂层技术中，等离子体电解氧化（PEO）（或微弧氧化-MAO）占据独特地位。这种方法为金属表面的改性提供了一种具有成本效益和环保的方法。PEO 可以有效地在轻合金上形成多孔、耐腐蚀和生物活性涂层。多孔氧化表面结构欢迎有机分子，这可以显著提高植入物的耐腐蚀性并改善身体的生物反应。该综述考虑了金属植入物上新的组合 PEO-有机涂层在植入、耐腐蚀性和体外及体内生物活性方面的最关键方面。
