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茶管理通过调节宿主微生物群来促进免疫稳态。

Tea Administration Facilitates Immune Homeostasis by Modulating Host Microbiota.

机构信息

Haide College, Ocean University of China, Qingdao 266100, China.

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China.

出版信息

Nutrients. 2024 Oct 29;16(21):3675. doi: 10.3390/nu16213675.

DOI:10.3390/nu16213675
PMID:39519508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11547558/
Abstract

Tea, derived from the young leaves and buds of the plant, is a popular beverage that may influence the host microbiota. Its consumption has been shown to promote the growth of beneficial bacterial species while suppressing harmful ones. Simultaneously, host bacteria metabolize tea compounds, resulting in the production of bioactive molecules. Consequently, the health benefits associated with tea may stem from both the favorable bacteria it nurtures and the metabolites produced by these microbes. The gut microbiota plays a vital role in mediating the systemic immune homeostasis linked to tea consumption, functioning through complex pathways that involve the gut-lung, gut-brain, and gut-liver axes. Recent studies have sought to establish connections between tea, its bioactive compounds, and immune regulation via the gut microbiota. In this paper, we aim to summarize the latest research findings in this field.

摘要

茶源于植物的嫩叶和芽,是一种受欢迎的饮品,可能会影响宿主微生物群。研究表明,它的摄入可以促进有益细菌的生长,同时抑制有害细菌。同时,宿主细菌代谢茶中的化合物,产生具有生物活性的分子。因此,茶带来的健康益处可能既源于其培养的有益细菌,也源于这些微生物产生的代谢物。肠道微生物群在介导与茶消费相关的系统性免疫稳态方面发挥着重要作用,其作用途径复杂,涉及肠道-肺、肠道-脑和肠道-肝轴。最近的研究试图通过肠道微生物群来建立茶、其生物活性化合物与免疫调节之间的联系。在本文中,我们旨在总结该领域的最新研究成果。

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本文引用的文献

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BMC Complement Med Ther. 2024 Oct 3;24(1):351. doi: 10.1186/s12906-024-04643-7.
2
Black Tea Suppresses Invasiveness and Reverses TNF-α-Induced Invasiveness and Cell Stemness in Human Malignant Melanoma Cells.红茶抑制人恶性黑色素瘤细胞的侵袭性,并逆转肿瘤坏死因子-α诱导的侵袭性和细胞干性。
Environ Toxicol. 2025 Feb;40(2):165-178. doi: 10.1002/tox.24423. Epub 2024 Sep 26.
3
Chemical profile and bioactivities of three types of yellow teas processed from different tenderness of young shoots of Huoshanjinjizhong ( var. ).
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Food Chem X. 2024 Sep 2;24:101809. doi: 10.1016/j.fochx.2024.101809. eCollection 2024 Dec 30.
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Changes in lipids and medium- and long-chain fatty acids during the spontaneous fermentation of ripened pu-erh tea.成熟普洱茶自然发酵过程中脂质及中长链脂肪酸的变化
Curr Res Food Sci. 2024 Aug 28;9:100831. doi: 10.1016/j.crfs.2024.100831. eCollection 2024.
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