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老年髋部骨折的年死亡率何时恢复到基线水平?

When does annual geriatric hip fracture mortality revert to baseline?

作者信息

Bernstein Joseph, Lee Alexander, Ahn Jaimo

机构信息

Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center, Philadelphia, PA, United States.

Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

Front Surg. 2024 Oct 25;11:1359648. doi: 10.3389/fsurg.2024.1359648. eCollection 2024.

Abstract

BACKGROUND

Geriatric hip fracture patients exhibit high mortality post-injury. It's unclear if and when mortality reverts to baseline. We therefore ask, When, if ever, does the mortality rate of geriatric hip fracture revert to the population-wide baseline rate? How does the mortality rate after geriatric hip fracture compare to the population norms? Understanding this timeline is crucial for assessing disease burden and guiding treatment plans.

METHODS

A cohort of 17,868 male patients aged 65-89 years treated for hip fracture within the VA healthcare system was studied. Patients were grouped by age at the time of fracture, and age-specific fractional survival was assessed annually for 10 years. For a comparison control group, a virtual cohort of 17,868 individuals, mirroring the age distribution of the patient group, was created and reduced over 10 cycles according to Social Security Administration expected mortality statistics.

RESULTS

The year-one mortality rate among fracture patients was 35.4%, compared to 6.3% in age-matched controls. By year ten, only 8.5% of the fracture patients remained alive, vs. 39.8% in the general population. The annual risk of dying for patients who survived past the first year was consistently in the range 19%-21% for all subsequent years.

CONCLUSION

Hip fracture patients who survive the initial injury are still subject to annual mortality risk of approximately 20%, an elevation above population norms persisting for at least a decade. The data underscores the severity of geriatric hip fractures, and suggest that focusing one- or two-year survival rates may not fully capture the severity of the injury.

摘要

背景

老年髋部骨折患者伤后死亡率较高。目前尚不清楚死亡率是否以及何时会恢复到基线水平。因此,我们提出以下问题:老年髋部骨折患者的死亡率何时(如果有的话)会恢复到全人群的基线水平?老年髋部骨折后的死亡率与人群标准相比如何?了解这一时间线对于评估疾病负担和指导治疗计划至关重要。

方法

对退伍军人医疗保健系统中17868名年龄在65 - 89岁之间接受髋部骨折治疗的男性患者进行了队列研究。患者按骨折时的年龄分组,并对10年期间每年的年龄特异性生存率进行评估。为了设立一个比较对照组,创建了一个由17868名个体组成的虚拟队列,该队列反映了患者组的年龄分布,并根据社会保障局的预期死亡率统计数据在10个周期内进行缩减。

结果

骨折患者的第一年死亡率为35.4%,而年龄匹配对照组为6.3%。到第十年,只有8.5%的骨折患者存活,而普通人群中这一比例为39.8%。在第一年之后存活的患者,其随后各年的年死亡风险始终在19% - 21%的范围内。

结论

在初始损伤中存活下来的髋部骨折患者每年仍面临约20%的死亡风险,这一高于人群标准的风险至少持续十年。这些数据凸显了老年髋部骨折的严重性,并表明关注一两年的生存率可能无法完全体现损伤的严重程度。

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