• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

调节尿酸。

Regulating uric acid.

机构信息

College of Animal Sciences, Zhejiang University, Hangzhou, China.

出版信息

Elife. 2024 Nov 11;13:e104493. doi: 10.7554/eLife.104493.

DOI:10.7554/eLife.104493
PMID:39526888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11554302/
Abstract

Certain strains of a bacterium found in the gut of some animals, , are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.

摘要

某些在某些动物肠道中发现的细菌菌株能够对抗高尿酸血症,这是一种由血液中尿酸水平过高引起的病症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11554302/31ed29aad942/elife-104493-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11554302/31ed29aad942/elife-104493-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11554302/31ed29aad942/elife-104493-fig1.jpg

相似文献

1
Regulating uric acid.调节尿酸。
Elife. 2024 Nov 11;13:e104493. doi: 10.7554/eLife.104493.
2
Host-derived alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides.内源性物质通过改善肠道微生物群落和水解酶介导的嘌呤核苷降解来缓解高尿酸血症。
Elife. 2024 Nov 7;13:e100068. doi: 10.7554/eLife.100068.
3
Tryptophan Metabolism-Regulating Probiotics Alleviate Hyperuricemia by Protecting the Gut Barrier Integrity and Enhancing Colonic Uric Acid Excretion.色氨酸代谢调节益生菌通过保护肠道屏障完整性和增强结肠尿酸排泄来缓解高尿酸血症。
J Agric Food Chem. 2024 Dec 4;72(48):26746-26761. doi: 10.1021/acs.jafc.4c07716. Epub 2024 Nov 20.
4
supplementation ameliorates hyperuricemia modulating intestinal homeostasis and relieving inflammation.补充剂可改善高尿酸血症,调节肠道内稳态并缓解炎症。
Food Funct. 2023 Jun 19;14(12):5663-5677. doi: 10.1039/d2fo03411e.
5
Screening and characterization of purine nucleoside degrading lactic acid bacteria isolated from Chinese sauerkraut and evaluation of the serum uric acid lowering effect in hyperuricemic rats.从中国酸菜中分离的嘌呤核苷降解乳酸菌的筛选、鉴定及其对高尿酸血症大鼠血清尿酸降低作用的评价
PLoS One. 2014 Sep 3;9(9):e105577. doi: 10.1371/journal.pone.0105577. eCollection 2014.
6
Supplementation of (TCI227) Prevented Potassium-Oxonate-Induced Hyperuricemia in Rats.(TCI227)补充剂可预防尿酸氧酸盐诱导的大鼠高尿酸血症。
Nutrients. 2022 Nov 15;14(22):4832. doi: 10.3390/nu14224832.
7
and increased gut microbiota diversity and functionality, and mitigated , in a mouse model.并增加了肠道微生物群落的多样性和功能,并在小鼠模型中减轻了。
Benef Microbes. 2019 Apr 19;10(4):413-424. doi: 10.3920/BM2018.0074. Epub 2019 Apr 8.
8
Lactiplantibacillus plantarum enables blood urate control in mice through degradation of nucleosides in gastrointestinal tract.植物乳杆菌通过降解肠道核苷来控制小鼠血尿酸水平。
Microbiome. 2023 Jul 19;11(1):153. doi: 10.1186/s40168-023-01605-y.
9
Probiotic Lactobacillus fermentum TSF331, Lactobacillus reuteri TSR332, and Lactobacillus plantarum TSP05 improved liver function and uric acid management-A pilot study.益生菌发酵乳杆菌 TSF331、罗伊氏乳杆菌 TSR332 和植物乳杆菌 TSP05 改善肝功能和尿酸管理:一项初步研究。
PLoS One. 2024 Jul 24;19(7):e0307181. doi: 10.1371/journal.pone.0307181. eCollection 2024.
10
Antiobesity and Uric Acid-Lowering Effect of GKM3 in High-Fat-Diet-Induced Obese Rats.高脂饮食诱导肥胖大鼠的 GKM3 抗肥胖和降低尿酸作用。
J Am Coll Nutr. 2019 Sep-Oct;38(7):623-632. doi: 10.1080/07315724.2019.1571454. Epub 2019 Feb 22.

引用本文的文献

1
Hiding in plain sight: A new lymphoid organ discovered in zebrafish.隐匿于众目睽睽之下:斑马鱼中发现的一个新淋巴器官。
J Exp Med. 2025 Jun 2;222(6). doi: 10.1084/jem.20250321. Epub 2025 Apr 18.

本文引用的文献

1
Host-derived alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides.内源性物质通过改善肠道微生物群落和水解酶介导的嘌呤核苷降解来缓解高尿酸血症。
Elife. 2024 Nov 7;13:e100068. doi: 10.7554/eLife.100068.
2
Quercetin-enriched Lactobacillus aviarius alleviates hyperuricemia by hydrolase-mediated degradation of purine nucleosides.富含槲皮素的鸟乳杆菌通过水解酶介导的嘌呤核苷降解来缓解高尿酸血症。
Pharmacol Res. 2023 Oct;196:106928. doi: 10.1016/j.phrs.2023.106928. Epub 2023 Sep 16.
3
Lactiplantibacillus plantarum enables blood urate control in mice through degradation of nucleosides in gastrointestinal tract.
植物乳杆菌通过降解肠道核苷来控制小鼠血尿酸水平。
Microbiome. 2023 Jul 19;11(1):153. doi: 10.1186/s40168-023-01605-y.
4
X11 Ameliorates Hyperuricemia and Modulates Gut Microbiota in Mice.X11 可改善小鼠的高尿酸血症并调节其肠道微生物群。
Front Immunol. 2022 Jul 6;13:940228. doi: 10.3389/fimmu.2022.940228. eCollection 2022.
5
Effect and Potential Mechanism of Q7 on Hyperuricemia and .Q7对高尿酸血症的作用及潜在机制 以及 (原文此处不完整)
Front Nutr. 2022 Jul 6;9:954545. doi: 10.3389/fnut.2022.954545. eCollection 2022.
6
The potential of probiotics in the amelioration of hyperuricemia.益生菌在改善高尿酸血症中的潜力。
Food Funct. 2022 Mar 7;13(5):2394-2414. doi: 10.1039/d1fo03206b.
7
Gout.痛风。
Lancet. 2021 May 15;397(10287):1843-1855. doi: 10.1016/S0140-6736(21)00569-9. Epub 2021 Mar 30.
8
JL-3 isolated from "Jiangshui" ameliorates hyperuricemia by degrading uric acid.JL-3 从“江水”中分离得到,可通过降解尿酸来改善高尿酸血症。
Gut Microbes. 2021 Jan-Dec;13(1):1-18. doi: 10.1080/19490976.2021.1897211.
9
The gut microbiota as a target to control hyperuricemia pathogenesis: Potential mechanisms and therapeutic strategies.肠道微生物群作为控制高尿酸血症发病机制的靶点:潜在机制和治疗策略。
Crit Rev Food Sci Nutr. 2022;62(14):3979-3989. doi: 10.1080/10408398.2021.1874287. Epub 2021 Jan 22.
10
Hyperuricemia and Cardiovascular Disease.高尿酸血症与心血管疾病
Curr Pharm Des. 2019;25(6):700-709. doi: 10.2174/1381612825666190408122557.