Weiss Márcio B, Borges Ricardo M, Sullivan Peter, Domingues João P B, da Silva Francisco H S, Trindade Victória G S, Luo Shangwen, Orjala Jimmy, Crnkovic Camila M
Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, CEP 05508-000, São Paulo, SP, Brazil.
Instituto de Pesquisas de Produtos Naturais Walter Mors, Universidade Federal do Rio de Janeiro, CEP 21941-599, Rio de Janeiro, RJ, Brazil.
Nat Prod Rep. 2025 Jan 22;42(1):6-49. doi: 10.1039/d4np00040d.
Covering: 2010 to 2023Cyanobacterial natural products are a diverse group of molecules with promising biotechnological applications. This review examines the chemical diversity of 995 cyanobacterial metabolites reported from 2010 to 2023. A computational analysis using similarity networking was applied to visualize the chemical space and to compare the diversity of cyanobacterial metabolites among taxonomic orders and environmental sources. Key examples are highlighted, detailing their sources, biological activities, and discovery processes.
2010年至2023年
蓝藻天然产物是一类具有广阔生物技术应用前景的多样分子。本综述考察了2010年至2023年报道的995种蓝藻代谢产物的化学多样性。运用相似性网络进行计算分析，以可视化化学空间，并比较不同分类目和环境来源的蓝藻代谢产物的多样性。文中突出了关键实例，详细介绍了它们的来源、生物活性及发现过程。
