MMWR Morb Mortal Wkly Rep. 2024 Nov 14;73(45):1036-1042. doi: 10.15585/mmwr.mm7345a4.
Measles vaccination effectively prevents measles, a highly contagious disease that can cause severe complications and death and requires high population immunity to interrupt transmission. This report describes measles elimination progress during 2000-2023. During 2000-2023, an estimated 60.3 million measles deaths were averted by vaccination. However, despite commitment from all six World Health Organization regions to eliminate measles, no region has successfully achieved and maintained measles elimination as of the end of 2023. During the COVID-19 pandemic, estimated global coverage with the first dose of measles-containing vaccine (MCV1) declined to 81%, the lowest level since 2008. MCV1 coverage improved to 83% in 2022 but was unchanged in 2023. From 2022 to 2023, estimated measles cases increased 20% worldwide, from 8,645,000 to 10,341,000; the number of countries experiencing large or disruptive outbreaks increased from 36 to 57. Estimated measles deaths decreased 8%, from 116,800 in 2022 to 107,500 in 2023, primarily because an increased number of cases occurred in countries with lower risk for death. The stagnation in MCV1 coverage means millions of children remain unprotected, leading to increases in cases and outbreaks. Coverage with measles-containing vaccine (MCV) is lower, and measles incidence is higher, in low-income countries and countries experiencing fragile, conflict-affected, and vulnerable settings, which exacerbate inequities. Urgent and targeted efforts are needed to ensure that all children receive 2 MCV doses and that surveillance is strengthened to hasten progress toward measles elimination.
麻疹疫苗的有效接种可预防麻疹,麻疹是一种高度传染性疾病,可导致严重并发症和死亡,需要高人群免疫力才能中断传播。本报告描述了 2000 年至 2023 年期间消除麻疹的进展情况。在 2000 年至 2023 年期间,疫苗接种使估计 6030 万例麻疹死亡得以避免。然而,尽管所有六个世界卫生组织区域都承诺消除麻疹,但截至 2023 年底,没有一个区域成功实现并维持了麻疹消除。在新冠肺炎大流行期间,全球首剂含麻疹成分疫苗(MCV1)的估计覆盖率下降到 81%,为 2008 年以来的最低水平。2022 年,MCV1 覆盖率提高到 83%,但 2023 年没有变化。2022 年至 2023 年,全球麻疹病例估计增加了 20%,从 8645 万例增至 1034.1 万例;出现大流行或破坏性疫情的国家数量从 36 个增加到 57 个。麻疹死亡人数减少了 8%,从 2022 年的 11.68 万例降至 2023 年的 10.75 万例,主要原因是死亡率较低的国家的病例数增加。MCV1 覆盖率的停滞不前意味着仍有数百万儿童未得到保护,导致病例和疫情的增加。在低收入国家和脆弱、受冲突影响和易受影响的环境中,麻疹疫苗的覆盖率较低,麻疹发病率较高,这加剧了不平等现象。需要紧急和有针对性的努力,以确保所有儿童都能接种 2 剂麻疹疫苗,并加强监测,以加快消除麻疹的进展。