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失用症:从神经解剖通路到临床表现。

Apraxia: From Neuroanatomical Pathways to Clinical Manifestations.

机构信息

Department of Psychology, University of Konstanz, Konstanz, Germany.

Lurija Institute for Rehabilitation Science and Health Research, Kliniken Schmieder, Allensbach, Germany.

出版信息

Curr Neurol Neurosci Rep. 2024 Nov 16;25(1):1. doi: 10.1007/s11910-024-01391-6.

DOI:10.1007/s11910-024-01391-6
PMID:39549184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11569007/
Abstract

PURPOSE OF REVIEW

Apraxia typically involves impairments in gesture production and tool use, affecting daily life activities. This article reviews current conceptualizations and developments in diagnostic and therapy.

RECENT FINDINGS

Apraxia has been studied in various neurological conditions, particularly stroke and dementia, but recent studies show gesturing deficits in psychiatric populations as well. Promising results have emerged from integrative treatment approaches involving intensive practice of gestures or daily activities. However, several reviews have noted the only marginal progress in apraxia therapy research despite new technologies, like virtual reality and brain stimulation, offering fresh opportunities for assessment and therapy. Advances in lesion-symptom mapping and connectivity analyses led to more detailed neuroanatomical models emphasizing parallel and gradual processing. These models facilitate the understanding of underlying mechanisms of motor cognitive performance and its decline. Finally, the digital era prompts the need to study digital tool use in apraxia, with initial efforts underway.

摘要

目的综述

失用症通常涉及到手势生成和工具使用方面的障碍,影响日常生活活动。本文综述了当前在诊断和治疗方面的概念和进展。

最近的发现

失用症已在各种神经疾病中进行了研究,尤其是在中风和痴呆症中,但最近的研究表明,在精神科人群中也存在手势缺陷。综合治疗方法,包括对手势或日常活动进行强化练习,已经取得了有希望的结果。然而,尽管虚拟现实和脑刺激等新技术为评估和治疗提供了新的机会,但仍有几项综述指出,失用症治疗研究进展甚微。在病变-症状映射和连接性分析方面的进展导致了更详细的神经解剖模型,强调了平行和渐进的处理。这些模型有助于理解运动认知表现及其下降的潜在机制。最后,数字时代促使人们需要研究失用症中的数字工具使用,目前已经在进行初步的努力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e472/11569007/b4fc4c650d50/11910_2024_1391_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e472/11569007/b4fc4c650d50/11910_2024_1391_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e472/11569007/b4fc4c650d50/11910_2024_1391_Fig1_HTML.jpg

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本文引用的文献

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The neural correlates of limb apraxia: An anatomical likelihood estimation meta-analysis of lesion-symptom mapping studies in brain-damaged patients.肢体失用症的神经相关性:脑损伤患者病变-症状映射研究的解剖似然估计荟萃分析。
Neurosci Biobehav Rev. 2024 Jul;162:105720. doi: 10.1016/j.neubiorev.2024.105720. Epub 2024 May 15.
2
Diagnosing homo digitalis: towards a standardized assessment for digital tool competencies.诊断数字素养:迈向数字工具能力的标准化评估
Front Psychol. 2024 Jan 4;14:1270437. doi: 10.3389/fpsyg.2023.1270437. eCollection 2023.
3
Active inference as a theory of sentient behavior.
主动推断:一种有感知行为的理论。
Biol Psychol. 2024 Feb;186:108741. doi: 10.1016/j.biopsycho.2023.108741. Epub 2024 Jan 3.
4
Does spatial perspective in virtual reality affect imitation accuracy in stroke patients?虚拟现实中的空间视角会影响中风患者的模仿准确性吗?
Front Virtual Real. 2022;3. doi: 10.3389/frvir.2022.934642. Epub 2022 Sep 7.
5
Investigation of Apraxia in Patients with Schizophrenia and Bipolar Disorder Type I.精神分裂症和 I 型双相情感障碍患者失用症的调查。
Psychiatr Danub. 2023 Spring;35(1):47-55. doi: 10.24869/psyd.2023.47.
6
Limb apraxia in individuals with multiple sclerosis: Is there a role of semi-immersive virtual reality in treating the Cinderella of neuropsychology?多发性硬化症患者的肢体失用症:半沉浸式虚拟现实在治疗神经心理学的灰姑娘中有作用吗?
Mult Scler Relat Disord. 2023 Jan;69:104405. doi: 10.1016/j.msard.2022.104405. Epub 2022 Nov 9.
7
The dementia apraxia test can detect early-onset Alzheimer's disease.痴呆失用症测试可以检测早发性阿尔茨海默病。
Neuropsychology. 2023 Jan;37(1):44-51. doi: 10.1037/neu0000873. Epub 2022 Nov 14.
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The dual-loop model for combining external and internal worlds in our brain.大脑中结合外部世界和内部世界的双环模型。
Neuroimage. 2022 Nov;263:119583. doi: 10.1016/j.neuroimage.2022.119583. Epub 2022 Aug 22.
9
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Dement Geriatr Cogn Disord. 2022;51(3):271-278. doi: 10.1159/000525618. Epub 2022 Jul 18.
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