Ahmad Farooq, Haq Anwarul, Khan Sher Wali
Ikramullah, Associate Professor, Cardiology Unit, Lady Reading Hospital, Peshawar, Pakistan.
Farooq Ahmad Assistant Professor Cardiology Unit, Khyber Teaching Hospital, Peshawar, Pakistan.
Pak J Med Sci. 2024 Nov;40(10):2228-2232. doi: 10.12669/pjms.40.10.9499.
BACKGROUND & OBJECTIVE: Acute coronary syndrome (ACS) can be divided into subgroups of ST-segment elevation myocardial infarction (STEMI), Non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (USA). Patients diagnosed with NSTEMI are either treated conservatively or early invasive strategy is adopted. In NSTEMI it is believed that either one or more vessel is transiently occluded or that the blood flow is critically reduced in a patent vessel i.e. subtotal occlusion. This study was conducted to find the angiographic characteristics of NSTEMI patients undergoing coronary angiography.
This study was conducted in Department of Cardiology, Lady Reading Hospital Peshawar. It was Cross Sectional Study. Data was collected from 8th November 2022 to 8th May 2023. Consecutive non-probability sampling technique was used to collect data from the patients.
Total of 300 patients were studied. The mean age was 56.95 years ±1.176 standard deviation. Male patients were 201 (67%) and remaining were female. It was found that 51(17%) of total NSTEMI patients were having totally obstructed coronary artery (OCA) in one or more coronary arteries. In NSTEMI, non-obstructive CAD (<50%) were found in 81 (27%) of patients whereas 219 (73%) were having significant CAD. It was found that 40% were having single vessel CAD, 32% were having double vessel CAD and 28% were having triple vessel CAD. TVCAD was present significantly higher in advance age, Diabetes mellitus, hyperlipidemia and family history of CAD.
Patients having NSTEMI are usually having multiple risk factors and having usually severe and multivessel CAD.
急性冠状动脉综合征(ACS)可分为ST段抬高型心肌梗死(STEMI)、非ST段抬高型心肌梗死(NSTEMI)和不稳定型心绞痛(USA)亚组。被诊断为NSTEMI的患者要么接受保守治疗,要么采用早期侵入性策略。在NSTEMI中,人们认为要么一根或多根血管短暂闭塞,要么一根通畅血管的血流严重减少,即次全闭塞。本研究旨在找出接受冠状动脉造影的NSTEMI患者的血管造影特征。
本研究在白沙瓦雷丁夫人医院心脏病科进行。这是一项横断面研究。数据收集于2022年11月8日至2023年5月8日。采用连续非概率抽样技术从患者中收集数据。
共研究了300例患者。平均年龄为56.95岁±1.176标准差。男性患者201例(67%),其余为女性。发现总共51例(17%)NSTEMI患者的一根或多根冠状动脉存在完全阻塞性冠状动脉(OCA)。在NSTEMI中,81例(27%)患者存在非阻塞性CAD(<50%),而219例(73%)存在显著CAD。发现40%的患者为单支血管CAD,32%为双支血管CAD,28%为三支血管CAD。在高龄、糖尿病、高脂血症和CAD家族史患者中,三支血管CAD的发生率显著更高。
患有NSTEMI的患者通常有多种危险因素,且通常患有严重的多支血管CAD。