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NACA 评分可预测入院前多发伤患者的死亡率:一项基于注册的研究。

The NACA score predicts mortality in polytrauma patients before hospital admission: a registry-based study.

机构信息

Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Via Tesserete 46, 6900, Lugano, Switzerland.

Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.

出版信息

Scand J Trauma Resusc Emerg Med. 2024 Nov 18;32(1):116. doi: 10.1186/s13049-024-01281-3.

Abstract

BACKGROUND

The early assessment of the severity of polytrauma patients is key for their optimal management. The aim of this study was to investigate the discriminative performance of the NACA score in a large dataset by stratifying the severity of polytraumatized patients in correlation to injury severity score (ISS), Glasgow Coma Scale (GCS), and mortality.

METHODS

This study on the Swiss Trauma Registry investigated 2239 polytraumatized patient (54.3 ± 22.8 years) enrolled from 2015 to 2023: 0.5% were NACA 3, 76.7% NACA 4, 21.4% NACA 5, and 1.4% NACA 6. The NACA predictive value of patients' mortality was investigated, as well as the correlation of ISS and GCS scores, and other factors influencing patients' survival at discharge and after 28 days.

RESULTS

In NACA 4 and 5 the survival rate during hospitalization was 97.7% and 82.5%, respectively, and 28-day mortality 3.5% and 23.5%, respectively (p < 0.0005). NACA correlated with GCS in the prehospital phase and in the emergency room (p < 0.0005), as well as with ISS (p < 0.0005). NACA 4 and 5 presented different injury patterns (fall < 3 m vs vehicle accident) with NACA 5 requiring more CPR and intubation (p < 0.001, p < 0.0005). The ROC AUC analysis showed the prehospital NACA and GCS values as the strongest variables predicting patients' survival.

CONCLUSIONS

This study provides valuable evidence supporting the effectiveness of the NACA score in assessing the severity of polytrauma patients in both the pre-ER and ER condition. Considering the statistical significant correlation with the GCS and with the ISS, NACA is a valid score for assessing polytrauma patients.

摘要

背景

早期评估多发伤患者的严重程度是对其进行最佳治疗的关键。本研究旨在通过与损伤严重程度评分(ISS)、格拉斯哥昏迷评分(GCS)和死亡率相关联,对 NACA 评分在大型数据集的区分性能进行分层,以研究多发伤患者的严重程度。

方法

本研究对瑞士创伤登记处的 2239 例多发伤患者(54.3±22.8 岁)进行了研究,纳入时间为 2015 年至 2023 年:0.5%为 NACA 3 级,76.7%为 NACA 4 级,21.4%为 NACA 5 级,1.4%为 NACA 6 级。研究了 NACA 对患者死亡率的预测价值,以及 ISS 和 GCS 评分的相关性,以及其他影响患者出院和 28 天后生存的因素。

结果

NACA 4 级和 5 级患者的住院期间生存率分别为 97.7%和 82.5%,28 天死亡率分别为 3.5%和 23.5%(p<0.0005)。NACA 在院前阶段和急诊室与 GCS 相关(p<0.0005),与 ISS 也相关(p<0.0005)。NACA 4 级和 5 级患者的损伤模式不同(<3 米的坠落伤与车辆事故),NACA 5 级患者需要更多的心肺复苏和插管(p<0.001,p<0.0005)。ROC AUC 分析显示,院前 NACA 和 GCS 值是预测患者生存的最强变量。

结论

本研究提供了有价值的证据,支持 NACA 评分在评估急诊前和急诊期间多发伤患者严重程度的有效性。考虑到与 GCS 和 ISS 的显著相关性,NACA 是评估多发伤患者的有效评分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dec/11575110/387b1b4a96d2/13049_2024_1281_Fig1_HTML.jpg

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