Biju Praisy B, Chaudhary Raushan Kumar, Radhakrishnan Krishnapriya, Shetty Shraddha, Mateti Uday Venkat, Raju Barma Naga, Sonkusare Shipra
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), NITTE (Deemed to be University), Mangalore, Karnataka 575018 India.
Department of Obstetrics and Gynaecology, KS Hegde Medical Academy (KSHEMA), Justice KS Hegde Charitable Hospital, NITTE (Deemed to be University), Mangalore, Karnataka 575018 India.
J Obstet Gynaecol India. 2024 Oct;74(5):447-453. doi: 10.1007/s13224-023-01893-2. Epub 2023 Dec 16.
To determine the occurrence of gestational diabetes mellitus and analyze the maternal and fetal outcomes among pregnant women.
A prospective cross-sectional study was conducted for a duration of 7 months in the Department of Gynecology and Obstetrics at tertiary care hospital where 518 pregnant women participants of age above 18 years who had come for labor and undergone DIPSI (diabetes in pregnancy study of India) test were included in the study after the ethical clearance and obtaining written informed consent, whereas pregnant women with pre-existing diabetes mellitus and on other medication that alter glucose metabolism were excluded from the study.
The occurrence of GDM was found to be 15.44%. The majority of GDM patients (53.75%) were able to manage their condition through dietary modifications alone. Metformin was required for 36.25% of the subjects, while 10% needed insulin. The rates of cesarean delivery (72.1%) and postpartum hemorrhage (17.5%) were also higher in the GDM group compared to the non-GDM group ( < 0.001). Maternal complications, including gestational hypertension (11.3%), polyhydramnios (35%), and vaginal candidiasis (18.8%), were significantly more prevalent among GDM subjects ( < 0.001).
GDM is a frequently observed complication among pregnant women which can lead to adverse maternal and fetal outcomes as well as several complications such as cesarean delivery, postpartum hemorrhage, pre-eclampsia, polyhydramnios, UTI and vaginal candidiasis as compared to those without GDM.
确定妊娠期糖尿病的发生率,并分析孕妇的母婴结局。
在一家三级护理医院的妇产科进行了为期7个月的前瞻性横断面研究。纳入了518名年龄在18岁以上前来分娩并接受了印度妊娠期糖尿病研究(DIPSI)测试的孕妇,研究经过伦理审查并获得书面知情同意。而患有既往糖尿病且正在服用其他改变葡萄糖代谢药物的孕妇被排除在研究之外。
发现妊娠期糖尿病的发生率为15.44%。大多数妊娠期糖尿病患者(53.75%)仅通过饮食调整就能控制病情。36.25%的受试者需要二甲双胍,而10%的人需要胰岛素。与非妊娠期糖尿病组相比,妊娠期糖尿病组的剖宫产率(72.1%)和产后出血率(17.5%)也更高(<0.001)。妊娠期糖尿病患者中,包括妊娠期高血压(11.3%)、羊水过多(35%)和阴道念珠菌病(18.8%)在内的母体并发症明显更为普遍(<0.001)。
妊娠期糖尿病是孕妇中常见的并发症,与非妊娠期糖尿病孕妇相比会导致不良的母婴结局以及剖宫产、产后出血、子痫前期、羊水过多、尿路感染和阴道念珠菌病等多种并发症。