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多队列人乳头瘤病毒疫苗接种对30岁以下女性宫颈癌的影响:来自斯堪的纳维亚国家的经验教训

Impact of Multicohort Human Papillomavirus Vaccination on Cervical Cancer in Women Below 30 Years of Age: Lessons Learned From the Scandinavian Countries.

作者信息

Nygård Ståle, Hetland Falkenthal Thea Eline, Sture Tina, Lynge Elsebeth, Elfström Miriam, Nygård Mari

机构信息

Department of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.

Zealand University Hospital, Nykøbing Falster, Denmark.

出版信息

J Infect Dis. 2025 Mar 17;231(3):e497-e500. doi: 10.1093/infdis/jiae584.

Abstract

In Scandinavia, human papillomavirus (HPV) vaccination programs started in 2007-2008 in Sweden and Denmark with HPV vaccination offered to multiple cohorts of young girls, while in Norway this was offered to a single cohort only. Interestingly, in Sweden and Denmark, cervical cancer incidence in young women decreased markedly from 2017 to 2018, while in Norway a steady increase was seen until 2020. As the 3 countries are very similar in other factors important for cervical cancer incidence rates, like cervical cancer screening, the observed difference is most likely due to differences in the multicohort vaccination.

摘要

在斯堪的纳维亚半岛,人乳头瘤病毒(HPV)疫苗接种计划于2007年至2008年在瑞典和丹麦启动,为多个年轻女孩群体提供HPV疫苗接种,而在挪威仅为一个群体提供。有趣的是,在瑞典和丹麦,年轻女性的宫颈癌发病率从2017年到2018年显著下降,而在挪威,直到2020年发病率一直在稳步上升。由于这三个国家在对宫颈癌发病率至关重要的其他因素(如宫颈癌筛查)方面非常相似,观察到的差异很可能是由于多群体疫苗接种的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7289/11911778/9df39dd4c614/jiae584f1.jpg

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