Sforzo Gary A, Gordon Neil F, Peeke Pamela M, Moore Margaret
School of Health Science and Human Performance, Ithaca College, Ithaca, NY, USA (GAS).
Intervent, Savannah, GA, USA (NFG).
Am J Lifestyle Med. 2024 Nov 19:15598276241302273. doi: 10.1177/15598276241302273.
Glucagon-like peptide agonists (GLP-1) are highly effective anti-obesity medications. However, sustained effectiveness is potentially plagued by lack of adherence to the drug and resumption of pre-weight loss behaviors. Side effects are primarily severe gastrointestinal distress but can occasionally be more serious. Health and well-being coaching (HWC) is an important obesity intervention that can be used alongside GLP-1 prescription. HWC is documented to improve medication adherence and promote healthy behavior change. A coach who understands the complexities of rapid weight loss, specifically with GLP-1, can help the patient persist with the treatment. Moreover, the coach can assist in navigating GLP-1 side effects including undesirable loss of skeletal muscle during the weight loss period. A patient-centric and collaborative relationship seem essential to the HWC process. Specific coaching techniques are suggested for working with patients losing weight. The logical, but yet to be tested, expectation is that HWC as an adjuvant intervention to GLP-1 prescription will improve medication adherence and encourage sustained weight loss and health benefits in patients with obesity.
胰高血糖素样肽激动剂(GLP-1)是非常有效的抗肥胖药物。然而,持续有效性可能受到药物依从性差和恢复减肥前行为的困扰。副作用主要是严重的胃肠道不适,但偶尔可能更严重。健康与幸福指导(HWC)是一种重要的肥胖干预措施,可与GLP-1处方一起使用。有文献证明,HWC可提高药物依从性并促进健康行为改变。了解快速减肥复杂性(特别是使用GLP-1时)的指导人员可以帮助患者坚持治疗。此外,指导人员可以协助应对GLP-1的副作用,包括减肥期间骨骼肌意外流失。以患者为中心的合作关系似乎对HWC过程至关重要。建议采用特定的指导技巧来帮助减肥患者。合理但尚未经过检验的期望是,HWC作为GLP-1处方的辅助干预措施,将提高药物依从性,并鼓励肥胖患者持续减肥并获得健康益处。