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脂磷壁酸的临界胶束浓度。

Critical micelle concentrations of lipoteichoic acids.

作者信息

Wicken A J, Evans J D, Knox K W

出版信息

J Bacteriol. 1986 Apr;166(1):72-7. doi: 10.1128/jb.166.1.72-77.1986.

Abstract

Purified lipoteichoic acids (LTAs) from several gram-positive organisms have been shown, by methods involving spectral changes of an added merocyanine dye probe, to have critical micelle concentrations in the range of 1 to 10 micrograms/ml, suggesting that acylated LTAs in their monomer forms may represent the major configuration of extracellular LTAs in bacterial culture fluids. The critical micelle concentrations obtained did not differ markedly with degree of carbohydrate substitution of the polymers. The significance of these findings in relation to the biological properties of LTA is discussed.

摘要

通过涉及添加部花青染料探针光谱变化的方法表明,从几种革兰氏阳性菌中纯化得到的脂磷壁酸(LTA),其临界胶束浓度在1至10微克/毫升范围内,这表明单体形式的酰化LTA可能是细菌培养液中细胞外LTA的主要存在形式。所得到的临界胶束浓度与聚合物的碳水化合物取代程度并无显著差异。本文讨论了这些发现与LTA生物学特性的相关性。

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