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探索在伊拉克流离失所人群中使用新冠病毒抗原快速诊断检测:来自四个境内流离失所者营地试点项目的结果

Exploring the use of COVID-19 antigen rapid diagnostic tests among displaced populations in Iraq: findings from a pilot project in four IDP camps.

作者信息

Ammar Lara Abou, Wolfe Caitlin M, Nagib Lamiaa, Slebei Mohammed, Shawkat Sezan, Amo Dilman, Abdullah Raveen, Abdulmalik Rawshan, Amin Hiwa Muhammed, Shafiq Huda, Hafthalah Shivan, Qahraman Aso, Mohammed Jirjees, Ghawji Hassan, Satyanarayana Srinath, Wilson Nevin, Sarin Sanjay, Kao Kekeletso, Ghusayni Nellie

机构信息

Migration Health Division, International Organization for Migration, IOM, Baghdad, Iraq.

College of Public Health, University of South Florida, Tampa, FL, USA.

出版信息

Confl Health. 2024 Nov 24;18(1):71. doi: 10.1186/s13031-024-00623-3.

Abstract

BACKGROUND

IOM piloted the use of Ag RDTs for COVID-19 in Iraq, in collaboration with FIND, the Global Alliance for Diagnostics, to facilitate access to testing and understand barriers and opportunities for testing in a displacement context. The purpose was to (i) evaluate the performance metrics of the Sure Status COVID-19 Antigen Card Test in this population; (ii) compare Ag RDT results across high- and low-probability cases, vaccination status, and symptom severity; and (iii) report participant perspectives on Ag RDT use for COVID-19 and other diseases.

METHODS

Secondary analysis was conducted using de-identified cross-sectional data collected from November 2022-March 2023 in four IDP camps in the Kurdistan region of Iraq. Data was collected during the recording, reporting, and monitoring processes of the pilot project using Ag RDTs for COVID-19 among displaced populations. Descriptive statistics and bivariate analyses were conducted in Stata (version 17).

RESULTS

9,346 Sure Status Ag RDTs were performed from November 2022-March 2023. Observed performance metrics were as follows: sensitivity = 72.73% (95% CI: 69.56-75.80%); specificity = 99.74% (95% CI: 99.39-100%), PPV = 92.31% (95% CI: 92.31-94.15%), and NPV = 98.85% (95% CI: 98.11-99.58%). Ag RDT uptake was higher among women and symptomatic individuals, and preference for Ag RDTs was especially strong among illiterate respondents. The overall positivity of Ag RDTs and PCR results in this population remained lower than national averages. Concerningly, 23.39% of respondents declined an Ag RDT because they did not believe in COVID-19.

CONCLUSIONS

This pilot program was among the first to explore Ag RDT use in Iraqi Kurdistan. Over 99% of respondents reported satisfaction with their experience, and over 90% wanted to see Ag RDTs available for other diseases. Findings can inform implementation of RDTs and screening protocols for other infectious diseases, and patient perspectives on Ag RDTs for testing and screening of COVID-19 among displaced populations can inform health programming within Iraq and globally.

摘要

背景

国际移民组织(IOM)与全球诊断联盟FIND合作,在伊拉克试点使用新冠病毒抗原快速检测试剂(Ag RDTs),以促进检测的可及性,并了解在流离失所背景下进行检测的障碍和机遇。目的是:(i)评估Sure Status新冠病毒抗原卡式检测在该人群中的性能指标;(ii)比较高概率和低概率病例、疫苗接种状况及症状严重程度的抗原快速检测结果;(iii)报告参与者对使用抗原快速检测试剂检测新冠病毒及其他疾病的看法。

方法

利用2022年11月至2023年3月在伊拉克库尔德地区四个境内流离失所者营地收集的匿名横断面数据进行二次分析。数据是在流离失所人群中使用新冠病毒抗原快速检测试剂的试点项目的记录、报告和监测过程中收集的。在Stata(版本17)中进行描述性统计和双变量分析。

结果

2022年11月至2023年3月共进行了9346次Sure Status抗原快速检测。观察到的性能指标如下:灵敏度=72.73%(95%置信区间:69.56 - 75.80%);特异性=99.74%(95%置信区间:99.39 - 100%),阳性预测值=92.31%(95%置信区间:92.31 - 94.15%),阴性预测值=98.85%(95%置信区间:98.11 - 99.58%)。女性和有症状者对抗原快速检测试剂的接受度更高,文盲受访者对抗原快速检测试剂的偏好尤为强烈。该人群中抗原快速检测试剂和聚合酶链反应结果的总体阳性率仍低于全国平均水平。令人担忧的是,23.39%的受访者拒绝进行抗原快速检测,因为他们不相信新冠病毒的存在。

结论

该试点项目是最早在伊拉克库尔德地区探索使用抗原快速检测试剂的项目之一。超过99%的受访者表示对检测体验满意,超过90%的受访者希望看到抗原快速检测试剂可用于检测其他疾病。研究结果可为其他传染病的快速检测试剂和筛查方案的实施提供参考,流离失所人群对抗原快速检测试剂用于新冠病毒检测和筛查的看法可为伊拉克及全球的卫生规划提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cec/11587649/68a000c52503/13031_2024_623_Fig1_HTML.jpg

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