Lipids and Cardiovascular Prevention Unit, Pinto University Health Centre, 28320 Madrid, Spain.
Department of Medicine, European University of Madrid, 28005 Madrid, Spain.
Nutrients. 2024 Nov 19;16(22):3948. doi: 10.3390/nu16223948.
BACKGROUND/OBJECTIVE: In addition to obesity, adiposity and abdominal obesity (AO) are parameters included in the cardiovascular-kidney-metabolic (CKM) syndrome. However, their prevalence and association with the other CKM factors have been less studied. Our study aimed to determine the prevalence rates of AO, high waist-to-height ratio (WtHR), and excess adiposity (EA), and to compare their associations with CKM factors.
A cross-sectional observational study was conducted with a random population-based sample of 6,588 study subjects between 18 and 102 years of age. Crude and sex- and age-adjusted prevalence rates of AO, high-WtHR, and EA were calculated, and their associations with CKM variables were assessed by bivariate and multivariate analyses.
The adjusted prevalence rates for AO, high-WtHR, and EA were 39.6% (33.6% in men; 44.9% in women), 30.6% (31.1% in men; 30.6% in women), and 65.6% (65.6% in men; 65.3% in women), respectively, and they increased with age. The main independent factors associated with AO, high-WtHR, and EA were hypertension, diabetes, prediabetes, low HDL-C, hypercholesterolaemia, hypertriglyceridemia, physical inactivity, hyperuricemia, and chronic kidney disease.
Two-thirds of the adult population have EA, one-third have AO, and one-third have high-WtHR. These findings support that the other factors of CKM syndrome, in addition to hyperuricemia and physical inactivity, show an independent association with these adiposity-related variables.
背景/目的:除肥胖外,体脂含量和腹型肥胖(AO)也是心血管-肾脏-代谢(CKM)综合征的参数。然而,它们的患病率及其与其他 CKM 因素的关系研究较少。本研究旨在确定 AO、高腰高比(WtHR)和超重肥胖(EA)的患病率,并比较它们与 CKM 因素的关系。
进行了一项横断面观察性研究,纳入了年龄在 18 至 102 岁之间的随机人群基础样本 6588 例。计算了 AO、高 WtHR 和 EA 的粗患病率和性别及年龄调整后患病率,并通过双变量和多变量分析评估了它们与 CKM 变量的关系。
AO、高 WtHR 和 EA 的调整后患病率分别为 39.6%(男性为 33.6%;女性为 44.9%)、30.6%(男性为 31.1%;女性为 30.6%)和 65.6%(男性为 65.6%;女性为 65.3%),且随年龄增长而增加。与 AO、高 WtHR 和 EA 主要相关的独立因素是高血压、糖尿病、糖尿病前期、低 HDL-C、高胆固醇血症、高三酰甘油血症、身体活动不足、高尿酸血症和慢性肾脏病。
三分之二的成年人口有 EA,三分之一有 AO,三分之一有高 WtHR。这些发现支持 CKM 综合征的其他因素,除了高尿酸血症和身体活动不足外,与这些与肥胖相关的变量存在独立关联。