Gothe R, Gold Y, Bezuidenhout J D
Onderstepoort J Vet Res. 1986 Mar;53(1):25-9.
Studies performed on sheep showed that Rhipicephalus evertsi mimeticus is a paralysis-competent tick species whose toxicity is either the same as, or only slightly less than that of R.e. evertsi. It was also proved that the paresis or paralysis induced by the mimeticus females is characterized by a constant incubation period which is independent of the tick infestation rate and body mass of the host, and consequently of its age. This period is entirely determined by the state of repletion of the ticks and is regulated by the date of mating. It was further proved that a precise relationship exists between an increase of engorgement or salivation activity and the intensity as well as the persistence of clinical symptoms. Thus only female ticks in the mass range of 15-21 mg are toxic. Strain-dependent differences could not be demonstrated. The infestation rates of subspecific hybrid female ticks, and of their descendants, that are necessary to produce the respective symptoms showed no differences in toxicity. When infestations were limited to a small skin area minimum paresis could frequently not be induced, even though the actual number of ticks applied was sufficient to cause lethal paralysis.
对绵羊进行的研究表明,埃氏扇头蜱拟态亚种是一种能够导致麻痹的蜱虫,其毒性与埃氏扇头蜱相同,或仅略低于后者。研究还证明,拟态亚种雌蜱引起的轻瘫或麻痹具有固定的潜伏期,该潜伏期与蜱虫的寄生率和宿主的体重无关,因此也与宿主年龄无关。这个时期完全由蜱虫的饱食状态决定,并受交配日期的调节。进一步证明,蜱虫饱食或唾液分泌活动的增加与临床症状的强度和持续时间之间存在精确的关系。因此,只有体重在15 - 21毫克范围内的雌蜱才具有毒性。未发现品系依赖性差异。产生相应症状所需的亚种杂交雌蜱及其后代的寄生率在毒性上没有差异。当寄生局限于小面积皮肤时,即使实际使用的蜱虫数量足以导致致命麻痹,也常常无法诱发最低程度的轻瘫。