Silva Elizeu Bruno Santos, Silva Maiza Conceição da, Araújo Maria Clara Santos, Paulino Beatriz Melo Santos Lima, Moraes-Junior José Maria Assunção, Torres Orlando Jorge Martins
From Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, Department of Gastrointestinal Surgery, Hepatopancreatobiliary and Liver Transplant Unit - São Luis (MA), Brazil.
Arq Bras Cir Dig. 2024 Dec 2;37:e1834. doi: 10.1590/0102-6720202400040e1834. eCollection 2024.
Pancreas divisum is an anatomical abnormality where the junction of the main and accessory pancreatic duct fails to occur and the smaller-caliber duct acts as dominant, resulting in overload during the drainage of the organ's secretion through the minor duodenal papilla.
To report a case of recurrent acute pancreatitis due to symptomatic pancreas divisum who underwent pancreatoduodenectomy.
A 21-year-old male patient presented with intermittent painful crises, located in the upper abdomen, with radiation to the back, associated with nausea and vomiting, for the past three years. Magnetic resonance imaging and endoscopic retrograde cholangiopancreatography revealed pancreas divisum, subsequently confirmed by endoscopic ultrasound. An attempt was made through endoscopic intervention but failed to catheterize the minor papilla; therefore, a pancreaticoduodenectomy was indicated. The organ was identified as hard and atrophied, with moderate peripancreatic inflammation. The histopathological findings also identified a focal well-differentiated G1-type neuroendocrine tumor measuring 0.4 cm.
In patients with pancreas divisum, rare cases may progress to recurrent acute pancreatitis. Pancreaticoduodenectomy is an option in symptomatic patients who had no success with endoscopic treatment.
胰腺分裂是一种解剖学异常,主胰管和副胰管未能汇合,较细的胰管起主导作用,导致通过十二指肠小乳头引流胰腺分泌物时负担过重。
报告一例因症状性胰腺分裂接受胰十二指肠切除术的复发性急性胰腺炎病例。
一名21岁男性患者在过去三年中出现间歇性疼痛发作,位于上腹部,可放射至背部,伴有恶心和呕吐。磁共振成像和内镜逆行胰胆管造影显示胰腺分裂,随后经内镜超声证实。曾尝试通过内镜干预,但未能成功插管至小乳头;因此,决定行胰十二指肠切除术。术中发现胰腺质地硬且萎缩,胰腺周围有中度炎症。组织病理学检查还发现一个直径0.4 cm的局灶性高分化G1型神经内分泌肿瘤。
在胰腺分裂患者中,罕见病例可能进展为复发性急性胰腺炎。对于内镜治疗无效的有症状患者,胰十二指肠切除术是一种选择。