Muminiy Sabina N, Harhash Tarek, Soni Aakash, Yunatanov Aron, Mordukhay Mark, Mavash Nathaniel, Ilyayeva Stella, Ilyaev Benjamin
Medicine, St. Francis College, Brooklyn , USA.
Medicine, Hofstra University, Hempstead, USA.
Cureus. 2024 Nov 7;16(11):e73200. doi: 10.7759/cureus.73200. eCollection 2024 Nov.
In the thyroid, abnormal growth can be the result of either benign thyroid nodules (BTNs) or differentiated thyroid cancers (DTCs). If the growth is confirmed to be a DTC, surgical intervention, either a partial or total thyroidectomy, is recommended. Although a majority of BTNs do not require treatment, intervention becomes necessary when nodules cause symptoms, enlargement, or a rare suspicion of malignancy. Clinical presentations of symptoms include psychological and aesthetic ones, such as a large lump on the neck, difficulty swallowing, pressure on the neck, and/or voice changes. The most common form of intervention for minimizing the volume of the BTN is surgery. However, due to several drawbacks to surgery and patient ineligibility, minimally invasive techniques such as radiofrequency ablation (RFA) have been recommended. Radiofrequency ablation serves as a minimally invasive non-surgical procedure that has been recognized to decrease the volume of BTNs. In the following case, we present a 50-year-old female patient with a growing multinodular goiter (MNG). A thyroid fine needle aspiration (FNA) biopsy and genetic testing confirmed the diagnosis of thyroid disease with possible malignancies. The nodule was increasing in size, causing discomfort, and possible malignancies were indicated by the FNA results. In order to avoid surgical intervention, the patient chose to undergo RFA, effectively decreasing the size of the BTN and dissipating the symptoms. This case highlights the effectiveness of RFA as a non-surgical alternative for treating benign MNG. Additionally, this case study provides insight into the unique treatment plans available for patients who opt out of surgery.
在甲状腺中,异常生长可能是良性甲状腺结节(BTN)或分化型甲状腺癌(DTC)所致。如果确诊为DTC,建议进行手术干预,即部分或全甲状腺切除术。虽然大多数BTN无需治疗,但当结节引起症状、肿大或罕见的恶性怀疑时,就需要进行干预。症状的临床表现包括心理和美观方面的,如颈部有大肿块、吞咽困难、颈部有压迫感和/或声音改变。减少BTN体积最常见的干预形式是手术。然而,由于手术存在一些缺点且患者不符合手术条件,因此推荐了诸如射频消融(RFA)等微创技术。射频消融是一种微创非手术程序,已被认可可减小BTN的体积。在以下病例中,我们介绍了一名患有不断增大的多结节性甲状腺肿(MNG)的50岁女性患者。甲状腺细针穿刺抽吸(FNA)活检和基因检测确诊为可能患有恶性肿瘤的甲状腺疾病。结节在增大,引起不适,FNA结果显示可能存在恶性肿瘤。为避免手术干预,患者选择接受RFA,有效地减小了BTN的大小并消除了症状。该病例突出了RFA作为治疗良性MNG的非手术替代方法的有效性。此外,本病例研究为选择不进行手术的患者提供了独特治疗方案的见解。