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胃肠病学和肝病学随机对照试验主要作者中的性别、种族和地区差异

Gender, Race, and Regional Disparities in Leading Authorships of Gastroenterology and Hepatology Randomized Controlled Trials.

作者信息

Chander Subhash, Sorath Fnu, Mohammed Yaqub Nadeem, Parkash Om, Sadarat Fnu, Lohana Abhi Chand, Shiwlani Sheena

机构信息

Department of Pulmonary and Critical Care Medicine, Mayo Clinic Rochester, Rochester, MN, USA.

Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

J Gastrointest Cancer. 2024 Dec 19;56(1):34. doi: 10.1007/s12029-024-01161-0.

Abstract

BACKGROUND AND AIMS

To investigate gender, racial, ethnic, and regional disparities in first and senior authorship positions in gastroenterology/hepatology-related randomised controlled trials (RCT).

METHOD

Retrospective bibliometric analysis of PubMed-indexed RCTs published between January 2000 to December 2022 in leading journals with an impact factor of at least five.

RESULTS

943 RCTs met our inclusion criteria, providing a participant pool of 301 female (15.96%) and 1,585 male (84.04%) authors from 37 countries (70% high-income countries). Despite a significant increase in the proportion of female authors in first and senior authorship positions between 2000 and 2022 (p<0.001), females were grossly underrepresented in both authorship positions, with a male-to-female ratio of 4.45 and 6.37, respectively. The male-to-female ratio was highest among Asian authors (7.79) than among White (4.22), Hispanic (1.44), and Black (1) authors in the first authorship position. In contrast, the male-to-female ratio was similar for Asian (6.2) and White (6.67) authors in the senior authorship position, with a low underlying frequency of Hispanic and Black female authors.

CONCLUSION

Despite significant improvements in gender, racial and ethnic representation in first and senior authorship of gastroenterology/hepatology-related RCTs published in high-impact journals, progress toward parity remains slow. Targeted interventions to improve author diversity are warranted.

摘要

背景与目的

研究胃肠病学/肝病学相关随机对照试验(RCT)中第一作者和资深作者职位的性别、种族、民族和地区差异。

方法

对2000年1月至2022年12月期间发表在影响因子至少为5的顶级期刊上、被PubMed收录的RCT进行回顾性文献计量分析。

结果

943项RCT符合我们的纳入标准,提供了来自37个国家(70%为高收入国家)的301名女性作者(15.96%)和1585名男性作者(84.04%)的参与样本。尽管2000年至2022年间,担任第一作者和资深作者职位的女性作者比例显著增加(p<0.001),但女性在这两个作者职位中的占比仍然极低,男性与女性的比例分别为4.45和6.37。在第一作者职位中,亚洲作者的男女比例最高(7.79),高于白人作者(4.22)、西班牙裔作者(1.44)和黑人作者(1)。相比之下,在资深作者职位中,亚洲作者(6.2)和白人作者(6.67)的男女比例相似,西班牙裔和黑人女性作者的潜在频率较低。

结论

尽管在高影响力期刊上发表的胃肠病学/肝病学相关RCT的第一作者和资深作者职位中,性别、种族和民族代表性有了显著改善,但实现平等的进展仍然缓慢。有必要采取针对性干预措施来提高作者的多样性。

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