Ji Wei, Fu Yuchen, Zheng Huifen, Li Yun
School of Communications and Information Engineering, Nanjing University of Posts and Telecommunications, Nanjing, Jiangsu 210003, China.
School of Communications and Information Engineering, Nanjing University of Posts and Telecommunications, Nanjing, Jiangsu 210003, China.
Comput Biol Med. 2025 Feb;185:109566. doi: 10.1016/j.compbiomed.2024.109566. Epub 2024 Dec 24.
Parkinson's Disease (PD) is the second-most common neurodegenerative disorder. There is a certain pathological connection between PD and dysphonia. Speech signals have been successfully used to identify PD and predict its severity. Moreover, PD has several subtypes, such as tremor, freezing of gait and dysphagia. The recognition of subtypes is of great significance for the diagnosis and treatment of PD. In this paper, we consider PD subtype recognition as a multi-label learning task and try to simultaneously recognize these subtypes using speech signals. In the proposed recognition framework, multiple types of speech data are collected, such as/a/,/pa-ka-la/, etc., and different speech features are extracted from different types of speech data. The features are concatenated as the representation of speech data. Especially, a multi-label speech feature selection algorithm based on graph structure is proposed to choose the key features and followed by a multi-label classifier for PD subtype recognition. The speech samples of 70 PD patients are collected as speech corpus. Experimental results show that the proposed multi-label feature selection method can obtain higher recognition performance than other classical ones in most cases.
帕金森病(PD)是第二常见的神经退行性疾病。PD与发声障碍之间存在一定的病理联系。语音信号已成功用于识别PD并预测其严重程度。此外,PD有几种亚型,如震颤、步态冻结和吞咽困难。亚型的识别对PD的诊断和治疗具有重要意义。在本文中,我们将PD亚型识别视为多标签学习任务,并尝试使用语音信号同时识别这些亚型。在所提出的识别框架中,收集了多种类型的语音数据,如/a/、/pa-ka-la/等,并从不同类型的语音数据中提取不同的语音特征。这些特征被连接起来作为语音数据的表示。特别是,提出了一种基于图结构的多标签语音特征选择算法来选择关键特征,然后使用多标签分类器进行PD亚型识别。收集了70名PD患者的语音样本作为语音语料库。实验结果表明,所提出的多标签特征选择方法在大多数情况下比其他经典方法能获得更高的识别性能。