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宫颈癌与HPV疫苗接种:阿尔巴尼亚女性的知识、态度及行为洞察

Cervical Cancer and HPV vaccination: Insights into knowledge, attitudes, and practices among Albanian women.

作者信息

Pojani Eftiola, Bozo Silvi, Capparelli Elena, Hoxha Bianka

机构信息

Department of Chemical-Pharmaceutical and Biomolecular Technologies, Faculty of Pharmacy, Catholic University "Our Lady of Good Counsel", Tirana, Albania.

出版信息

Vaccine X. 2024 Dec 5;22:100594. doi: 10.1016/j.jvacx.2024.100594. eCollection 2025 Jan.

Abstract

INTRODUCTION

Human papillomavirus (HPV) infection is a widespread skin-to-skin transmitted infection that poses a global health concern. Although Albania faced prior challenges, it has recently introduced a quadrivalent recombinant HPV vaccine, a critical step in preventing cervical cancer among young women. This study aims to identify potential gaps in knowledge and attitudes among Albanian women regarding cervical cancer and HPV infection, as well as provide insights into the effectiveness of the national primary prevention program.

METHODS

We conducted a cross-sectional study among 473 Albanian women using an anonymous online questionnaire to collect sociodemographic information, awareness on HPV infection and cervical cancer, and HPV vaccination practices. The association between sociodemographic variables and outcome measures was explored using descriptive statistics and Chi-square tests in SPSS.

RESULTS

Most of the participants fell within the age range of 18 to 30 years old (42.1 %). 71.7 % of the respondents lived in urban areas. According to the study findings, a considerable proportion of the participants demonstrated knowledge of cervical cancer, with 66.6 % correctly identifying HPV infection as a major cause of this disease. Additionally, the study uncovered that a substantial number of participants had an acceptable awareness (59.6 %) about the HPV vaccine. Nevertheless, 48.4 % of the participants expressed concerns about the vaccine's efficacy and safety.

CONCLUSIONS

The study reveals knowledge gaps and misconceptions about HPV transmission, hereditary aspects, and its connection to various cancers. While a positive attitude towards preventive measures exists, concerns about HPV vaccination safety and efficacy underscore the need for targeted education campaigns to enhance awareness and accessibility, addressing misconceptions and promoting informed decision-making for effective cervical cancer prevention.

摘要

引言

人乳头瘤病毒(HPV)感染是一种广泛传播的皮肤接触性感染,引起了全球健康关注。尽管阿尔巴尼亚此前面临挑战,但该国最近引入了四价重组HPV疫苗,这是预防年轻女性宫颈癌的关键一步。本研究旨在确定阿尔巴尼亚女性在宫颈癌和HPV感染方面的知识和态度潜在差距,并深入了解国家一级预防计划的有效性。

方法

我们对473名阿尔巴尼亚女性进行了一项横断面研究,使用匿名在线问卷收集社会人口学信息、对HPV感染和宫颈癌的认识以及HPV疫苗接种情况。在SPSS中使用描述性统计和卡方检验探索社会人口学变量与结果指标之间的关联。

结果

大多数参与者年龄在18至30岁之间(42.1%)。71.7%的受访者居住在城市地区。根据研究结果,相当一部分参与者对宫颈癌有一定了解,66.6%的人正确将HPV感染识别为该病的主要原因。此外,研究发现大量参与者对HPV疫苗有可接受的认识(59.6%)。然而,48.4%的参与者对疫苗的有效性和安全性表示担忧。

结论

该研究揭示了在HPV传播、遗传因素及其与各种癌症的关联方面存在知识差距和误解。虽然对预防措施持积极态度,但对HPV疫苗安全性和有效性的担忧凸显了开展有针对性的教育活动的必要性,以提高认识和可及性,消除误解并促进做出明智决策以有效预防宫颈癌。

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