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在不进行骶髂关节融合的成人脊柱畸形手术中维持腰骶-骨盆区域的稳定性:4枚骨盆螺钉是否优于2枚骨盆螺钉?

Maintaining stability at the lumbosacral-pelvic region in adult spinal deformity surgery without sacroiliac joint fusion: are 4 pelvic screws superior to 2 pelvic screws?

作者信息

Mohanty Sarthak, Stephan Stephen R, Mikhail Christopher, Platt Andrew, Bakhsheshian Joshua, Hassan Fthimnir M, Lewerenz Erik, Lombardi Joseph M, Sardar Zeeshan M, Lehman Ronald A, Lenke Lawrence G

机构信息

1Department of Orthopaedic Surgery, The Och Spine Hospital/Columbia University Irving Medical Center, New York, New York.

2Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

J Neurosurg Spine. 2024 Dec 27;42(3):320-330. doi: 10.3171/2024.8.SPINE231331. Print 2025 Mar 1.

Abstract

OBJECTIVE

The objective of this study was to compare a multiple pelvic screw fixation strategy (dual bilateral 4 pelvic screw fixation [4PvS]) with the use of single bilateral 2 pelvic screw fixation (2PvS), with the aim of addressing lumbosacral junction stability.

METHODS

This analysis is a single-center, retrospective review of ASD patients treated between 2015 and 2021. All patients had a minimum 2-year follow-up and spinal fusion to the sacrum without sacroiliac fusion and met at least one radiographic and procedural criterion: pelvic incidence-lumbar lordosis ≥ 20°, T1 pelvic angle ≥ 20°, sagittal vertical axis ≥ 7.5 cm, scoliosis ≥ 50°, three-column osteotomy, or spinal fusion of ≥ 8 levels. Two sacropelvic fixation methods were compared: 4PvS versus 2PvS. Primary outcomes included spinal implant-related reoperation and screw breakage, while secondary outcomes included reoperation for symptomatic pelvic screws, screw loosening or bending, L5-S1 pseudarthrosis, and patient-reported outcomes. Propensity score matching and inverse probability of treatment weighting (IPTW) were used to minimize selection bias and estimate causal treatment effects. Clinical outcomes were assessed using conditional multivariable logistic regression.

RESULTS

In this study of 406 patients (67.98% female, mean age 64.48 years), 349 patients (85.96%) received 2PvS and 57 (14.04%) received 4PvS. Age (OR 1.081, 95% CI 1.027-1.145) and total number of osteotomies (OR 1.180, 95% CI 1.048-1.355) emerged as independent predictors of receiving the 4PvS technique. In unmatched cohorts (n = 406), 2-year implant-related reoperation rates (p = 0.1896) and pelvic screw breakage rates (p = 0.2498) were not significantly different between groups. However, in the 4:1 propensity score-matched cohort, the 2-year reoperation rate (10.53% for 2PvS vs 3.51% for 4PvS; OR 3.27, 95% CI 1.10-9.74 [p = 0.0312]) and the pelvic screw breakage rate (9.21% for 2PvS vs 3.51% for 4PvS; OR 2.87, 95% CI 1.08-7.63 [p = 0.0349]) were significantly higher among the 2PvS groups. The IPTW analysis confirmed these findings, with reoperation rates of 10.45% for 2PvS and 1.18% for 4PvS (p = 0.0244) and pelvic screw breakage rates of 8.72% and 1.18%, respectively (p = 0.0477). A safety assessment revealed comparable operative times and intra- and perioperative complications between the two techniques.

CONCLUSIONS

Patients who underwent 4PvS demonstrated significantly lower 2-year implant-related reoperation and pelvic screw breakage rates compared with 2PvS, with no differences in intraoperative or perioperative complications.

摘要

目的

本研究的目的是比较一种多枚骨盆螺钉固定策略(双侧4枚骨盆螺钉固定[4PvS])与使用单侧双侧2枚骨盆螺钉固定(2PvS),以解决腰骶部连接稳定性问题。

方法

本分析是对2015年至2021年间接受治疗的成人脊柱畸形(ASD)患者进行的单中心回顾性研究。所有患者至少随访2年,且脊柱融合至骶骨,无骶髂关节融合,并符合至少一项影像学和手术标准:骨盆入射角-腰椎前凸≥20°,T1骨盆角≥20°,矢状垂直轴≥7.5 cm,脊柱侧凸≥50°,三柱截骨术,或≥8节段的脊柱融合。比较两种骶骨盆固定方法:4PvS与2PvS。主要结局包括与脊柱植入物相关的再次手术和螺钉断裂,而次要结局包括有症状的骨盆螺钉再次手术、螺钉松动或弯曲、L5-S1假关节形成以及患者报告的结局。使用倾向评分匹配和治疗权重逆概率(IPTW)来最小化选择偏倚并估计因果治疗效果。使用条件多变量逻辑回归评估临床结局。

结果

在本研究的406例患者中(67.98%为女性,平均年龄64.48岁),349例(85.96%)接受了2PvS,57例(14.04%)接受了4PvS。年龄(OR 1.081,95%CI 1.027-1.145)和截骨总数(OR 1.180,95%CI 1.048-1.355)是接受4PvS技术的独立预测因素。在未匹配队列(n = 406)中,两组之间2年与植入物相关的再次手术率(p = 0.1896)和骨盆螺钉断裂率(p = 0.2498)无显著差异。然而,在4:1倾向评分匹配队列中,2年再次手术率(2PvS为10.53%,4PvS为3.51%;OR 3.27,95%CI 1.10-9.74 [p = 0.0312])和骨盆螺钉断裂率(2PvS为9.21%,4PvS为3.51%;OR 2.87,95%CI 1.08-7.63 [p = 0.0349])在2PvS组中显著更高。IPTW分析证实了这些发现,2PvS的再次手术率为10.45%,4PvS为1.18%(p = 0.0244),骨盆螺钉断裂率分别为8.72%和1.18%(p = 0.0477)。安全性评估显示两种技术的手术时间以及术中和围手术期并发症相当。

结论

与2PvS相比,接受4PvS的患者2年与植入物相关的再次手术率和骨盆螺钉断裂率显著更低,术中和围手术期并发症无差异。

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