Zhang Hanyu, Hu Anbang, Li Yanling, Li Mingcui, Rong Zhiyuan, Cheng Weilun, Liu Yansong, Duan Yunqiang, Feng Jianyuan, Chen Ziang, Yu Tianshui, Zhang Jiarui, Wang Ting, Shang Yuhang, Fang Zhengbo, Liu Jiangwei, Kong Fanjing, Ma Fei, Guo Baoliang
Department of General Surgery, Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Street, Nangang District, Harbin, China.
Breast J. 2024 Dec 24;2024:5639017. doi: 10.1155/tbj/5639017. eCollection 2024.
Clinical management of papillary breast lesions (PBLs) remains controversial. Our objective was to analyze the independent risk factors associated with malignant PBLs. A retrospective review of clinical variables in 2964 patients with papillary lesions available for evaluation. This retrospective study screened that older patients (≥ 50 years), postmenopausal, palpable tumor, tumor size ≥ 15 mm, peripheral tumor, and tumor with calcification were independent risk factors affecting malignant PBLs. Moreover, the probability of malignant PBLs without the appealed risk factors was only 3.4%. Patients without risk factors for papillary lesions can manage their health with imaging surveillance. The choice of surgical treatment for the remaining patients is a reasonable recommendation.
乳腺乳头状病变(PBLs)的临床管理仍存在争议。我们的目的是分析与恶性PBLs相关的独立危险因素。对2964例有可供评估的乳头状病变患者的临床变量进行回顾性分析。这项回顾性研究筛查出年龄较大(≥50岁)、绝经后、可触及肿瘤、肿瘤大小≥15mm、周边型肿瘤以及伴有钙化的肿瘤是影响恶性PBLs的独立危险因素。此外,没有上述危险因素的PBLs发生恶性的概率仅为3.4%。没有乳头状病变危险因素的患者可通过影像学监测来管理自身健康。对于其余患者,手术治疗是合理的建议。