AMPAR Regulation in Synaptic Plasticity: The Roles of Calcineurin, CK2, and α2δ-1.
作者信息
Coca Richard
机构信息
Graduate Program for Neuroscience, Boston University, Boston, Massachusetts 02215
出版信息
J Neurosci. 2025 Jan 1;45(1):e1703242024. doi: 10.1523/JNEUROSCI.1703-24.2024.
Abstract
摘要
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本文引用的文献
1
Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons.钙调神经磷酸酶和 CK2 通过脊髓兴奋性神经元上的α2δ-1 相互调节突触 AMPA 受体表型。
J Neurosci. 2024 Jul 17;44(29):e0392242024. doi: 10.1523/JNEUROSCI.0392-24.2024.
2
Calcineurin regulates synaptic Ca-permeable AMPA receptors in hypothalamic presympathetic neurons via α2δ-1-mediated GluA1/GluA2 assembly.钙调神经磷酸酶通过 α2δ-1 介导的 GluA1/GluA2 组装调节下丘脑节前交感神经元中的突触钙通透性 AMPA 受体。
J Physiol. 2024 May;602(10):2179-2197. doi: 10.1113/JP286081. Epub 2024 Apr 17.
3
Single-cell RNA sequencing uncovers the cell type-dependent transcriptomic changes in the retrosplenial cortex after peripheral nerve injury.单细胞 RNA 测序揭示了外周神经损伤后隔区皮质中依赖细胞类型的转录组变化。
Cell Rep. 2023 Dec 26;42(12):113551. doi: 10.1016/j.celrep.2023.113551. Epub 2023 Dec 3.
4
Calcineurin-Inhibitor Induced Pain Syndrome in a Heart Transplant Patient.心脏移植患者的钙调神经磷酸酶抑制剂诱导痛综合征。
Transplant Proc. 2021 Oct;53(8):2630-2635. doi: 10.1016/j.transproceed.2021.08.014. Epub 2021 Sep 2.
5
α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly.α2δ-1通过物理性破坏异聚体亚基组装来改变突触AMPA受体的表型。
Cell Rep. 2021 Jul 20;36(3):109396. doi: 10.1016/j.celrep.2021.109396.
6
Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors.钙调神经磷酸酶通过钙离子通透型AMPA受体的突触转运介导突触缩放。
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7
Casein kinase 2 phosphorylates GluA1 and regulates its surface expression.酪蛋白激酶2使谷氨酸受体1亚基（GluA1）磷酸化并调节其表面表达。
Eur J Neurosci. 2014 Apr;39(7):1148-58. doi: 10.1111/ejn.12494.
8
Nerve injury increases GluA2-lacking AMPA receptor prevalence in spinal cords: functional significance and signaling mechanisms.神经损伤增加脊髓中 GluA2 缺失型 AMPA 受体的普遍性：功能意义和信号机制。
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GluA2-lacking, calcium-permeable AMPA receptors--inducers of plasticity?缺乏 GluA2 的、钙通透性的 AMPA 受体——是可塑性的诱导物？
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