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电灼术及胺碘酮可能引发心室颤动:一例罕见临床病例报告

Ventricular fibrillation likely resulting from electrocautery and amiodarone: a rare clinical case report.

作者信息

Guo Jianwei, Cheng Yan, Yi Minmin

机构信息

Department of Anesthesiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.

出版信息

J Int Med Res. 2025 Jan;53(1):3000605241310080. doi: 10.1177/03000605241310080.

Abstract

Monopolar electrocautery is usually a safe and effective technique used in laparoscopic cholecystectomy and bile duct surgery, but it may lead to adverse consequences, even ventricular fibrillation (VF). Amiodarone is an effective antiarrhythmic drug commonly used in practice to treat ventricular and atrial arrhythmias, but it may induce tachyarrhythmia or even VF. We report a case of VF occurring twice during cholecystectomy. The first VF was caused by low-frequency leakage current of the monopolar electrocautery. The second VF was due to amiodarone causing further prolongation of the corrected QT interval. By performing cardiopulmonary resuscitation and defibrillation, the patient recovered and was eventually discharged in good condition. In cholecystectomy surgery, especially when separating adhesive tissue from liver, caution should be exercised when using a monopolar electrotome, which is recommended to stop bleeding in the bipolar mode. After cardiopulmonary resuscitation, caution should be exercised when using amiodarone to prevent arrhythmia, even if prolongation of the corrected QT interval does not reach the diagnostic indicators of 470 ms for men and 480 ms for women. In addition, defibrillators should be in standby mode during the perioperative period.

摘要

单极电灼术通常是一种用于腹腔镜胆囊切除术和胆管手术的安全有效的技术,但它可能会导致不良后果,甚至心室颤动(VF)。胺碘酮是一种在实践中常用的有效抗心律失常药物,用于治疗室性和房性心律失常,但它可能诱发快速心律失常甚至VF。我们报告一例在胆囊切除术中发生两次VF的病例。第一次VF是由单极电灼术的低频漏电流引起的。第二次VF是由于胺碘酮导致校正QT间期进一步延长。通过进行心肺复苏和除颤,患者康复并最终康复出院。在胆囊切除术中,特别是在从肝脏分离粘连组织时,使用单极电刀时应谨慎,建议采用双极模式止血。心肺复苏后,即使校正QT间期延长未达到男性470毫秒、女性480毫秒的诊断指标,使用胺碘酮时也应谨慎,以防止心律失常。此外,围手术期除颤器应处于备用模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b24/11729417/5b09dd9b4bf8/10.1177_03000605241310080-fig1.jpg

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