Margaryan Viktoria, Aghasyan Eduard, Yessayan Lazar, Khachatryan Hakob, Bollen Curd, Hakobyan Gagik
Department of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan, Armenia.
Vivaldi Dental Clinic, Yerevan, Armenia.
Clin Oral Investig. 2025 Jan 23;29(1):78. doi: 10.1007/s00784-025-06163-1.
The aim of the study is to compare the clinical efficacy of the application of "Armenicum" paste as an adjunct to SRP for the non-surgical treatment of patients with periodontitis.
The current RCT prospective study was conducted on 157 patients with chronic periodontitis. The patients were blind randomly assigned into two groups: Group A (SRP + Armenicum" paste) 81 patients (42 males and 39 females, 37 to 68 years) and Group B (SRP) 76 patients (39 males and 37 females, 37 to 68 years). Periodontal indices BOP, PPD, and DPI within each treatment group were measured before periodontal therapy, 3 and 6 months after the treatment. Group A underwent a periodontal treatment which included: supragingival and subgingival scaling, and additional use of local "Armenicum" paste. The Group B group only received supragingival and subgingival scaling.
In our study, the mean BOP, DPI, and PPD showed a statistically significant difference from baseline to 3 months and 6 months (p ≤ 0.05) in both Group A and Group B. But, mean BOP and mean PPD reduction gain was found to be greater in Group-A than Group B at 3 months and 6 months. No statistical differences in clinical indices were recorded depending on gender and age.
These results indicate that topical "Armenicum" paste provides an effective adjunctive treatment of chronic periodontitis.
The results of the current study showed that the adjunctive use of "Armenicum" reduced signs of inflammation compared to standard SRP treatment alone. Periodontal therapy using Armenicum paste application can be considered as a promising method in the treatment of periodontitis.
本研究旨在比较“亚美尼亚糊剂”作为辅助治疗手段与龈下刮治术(SRP)联合应用于牙周炎患者非手术治疗的临床疗效。
对157例慢性牙周炎患者进行了本次随机对照试验前瞻性研究。患者被随机分为两组:A组(SRP +“亚美尼亚糊剂”)81例(男性42例,女性39例,年龄37至68岁)和B组(SRP)76例(男性39例,女性37例,年龄37至68岁)。在牙周治疗前、治疗后3个月和6个月测量每个治疗组的牙周指标牙龈出血指数(BOP)、探诊深度(PPD)和牙菌斑指数(DPI)。A组接受了牙周治疗,包括:龈上和龈下刮治,并额外使用局部“亚美尼亚糊剂”。B组仅接受龈上和龈下刮治。
在我们的研究中,A组和B组从基线到3个月和6个月时,平均BOP、DPI和PPD均显示出统计学上的显著差异(p≤0.05)。但是,在3个月和6个月时,A组的平均BOP和平均PPD降低幅度大于B组。未发现临床指标因性别和年龄而有统计学差异。
这些结果表明,局部应用“亚美尼亚糊剂”对慢性牙周炎有有效的辅助治疗作用。
当前研究结果表明,与单独的标准SRP治疗相比,“亚美尼亚糊剂”的辅助使用减少了炎症迹象。使用亚美尼亚糊剂进行牙周治疗可被视为治疗牙周炎的一种有前景的方法。