Suzuki M T, Narita H, Fukui M
Jikken Dobutsu. 1985 Jan;34(1):81-4. doi: 10.1538/expanim1978.34.1_81.
Three thousand and five apparently healthy cynomolgus monkeys (Macaca fascicularis) were examined for the finding of the anterior part of the oculi by using an ophthalmoscope. One drop of the mixed solution of 0.5% tropicamide and 0.5% phenylephrine hydrochloride was instilled into each eye of the animal. Then, those monkeys were anesthetized with ketamine-HC1 at the dose level of 10 mg/kg B. W.. One monkey had opaque membranes of tan to brown color, extending from some part of collarette of the iris to the other part of collarette like the network over the pupil. This finding was diagnosed to be bilateral persistent pupillary membranes. Further breeding studies will be carried to determine if this case in hereditary.
使用检眼镜对3050只外观健康的食蟹猴(猕猴)进行眼部前部检查。向每只动物的眼睛滴入一滴0.5%托吡卡胺和0.5%盐酸去氧肾上腺素的混合溶液。然后,用剂量为10mg/kg体重的氯胺酮-HC1对这些猴子进行麻醉。一只猴子有从虹膜小环的某些部分延伸到小环另一部分的棕褐色不透明膜,就像覆盖在瞳孔上的网络。这一发现被诊断为双侧永存瞳孔膜。将进行进一步的繁殖研究以确定该病例是否具有遗传性。