Lucchese Angelica Maria, Kalil Antonio Nocchi, Diniz Alessandro L, Oldhafer Karl J, Pawlik Timothy M, Adam René, Soubrane Olivier, Braghiroli Maria Ignez, Cotta-Pereira Ricardo Lemos
Irmandade Santa Casa de Misericórdia de Porto Alegre, Department of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation - Porto Alegre (RS), Brazil.
A. C. Camargo Cancer Center, Department of Abdominal Surgery - São Paulo (SP), Brazil.
Arq Bras Cir Dig. 2025 Jan 27;37:e1866. doi: 10.1590/0102-6720202400072e1866. eCollection 2025.
Liver metastases from melanomas, sarcomas, and renal tumors are less frequent. Treatment and prognosis will depend on whether they are isolated or multiple, size and location, the presence or absence of extrahepatic neoplastic disease, age, stage of the initial disease, initial treatments instituted, time of evolution, and clinical condition of the patient. Recently, a high number of oncological therapies including monotherapy or in combination, neoadjuvants or adjuvants, and immuno-oncological treatments have been developed and tested, increasing disease-free time and survival.
黑色素瘤、肉瘤和肾肿瘤的肝转移较少见。治疗方法和预后将取决于转移灶是孤立的还是多发的、大小和位置、是否存在肝外肿瘤性疾病、年龄、初始疾病的分期、所采取的初始治疗、病情发展时间以及患者的临床状况。最近,已经研发并测试了大量的肿瘤治疗方法,包括单药治疗或联合治疗、新辅助治疗或辅助治疗以及免疫肿瘤治疗,从而延长了无病生存期和总生存期。