Lombe Dorothy Chilambe, Mwamba Monde, Simwinga Musonda, Bond Virginia, Ssemata Andrew Sentoogo, Muhumuza Richard, Seeley Janet, Lishimpi Kennedy, Mapulanga Victor, Kachimba John, Aggarwal Ajay, Msadabwe Susan
Department of Radiation Oncology, MidCentral District Health Board, Palmerston North, New Zealand.
Zambart, School of Public Health, Ridgeway Campus, University of Zambia, Lusaka, Zambia.
BMJ Oncol. 2024 May 8;3(1):e000172. doi: 10.1136/bmjonc-2023-000172. eCollection 2024.
Locally led research on cancer is needed in sub-Saharan Africa to set feasible research priorities that inform national policy. The aim of this project was to develop a research agenda for national cancer control planning, using a nationally driven approach, focused on barriers to diagnosis and high-quality treatment for prostate cancer in Zambia.
This was a Delphi process. 29 stakeholders were scored barriers on feasibility, the proportion of patients affected, the impact on patient outcomes and if there was a potential to address health systems barriers meaningfully. There were three rounds (R) to the process: (R1 and R2) by electronic survey and (R3) in-person meeting. In R1 statements scoring above 15 from over 70% of participants were prioritised immediately for R3 discussion. Those scoring below 30% were dropped and those in between were re-surveyed in R2.
22 and 17 of the 29 stakeholders responded to R1 and R2. 14 stakeholders attended R3. National priority research areas for prostate cancer in Zambia were identified as prostate cancer awareness; building affordable high-quality diagnostic capacity; affordability of specialist cancer treatments; supporting better access to medicines; delivery and coordination of services across the pathway and staff training.
The suggested seven priority areas allow for the development of the prostate cancer control programme to be conducted in a holistic manner. The expectation is with this guidance international partners can contribute within the frameworks of the local agenda for sustainable development to be realised.
撒哈拉以南非洲地区需要开展由当地主导的癌症研究,以确定可行的研究重点,为国家政策提供依据。本项目的目的是采用国家驱动的方法,制定一项国家癌症控制规划的研究议程,重点关注赞比亚前列腺癌诊断和高质量治疗的障碍。
这是一个德尔菲法过程。29名利益相关者就可行性、受影响患者的比例、对患者预后的影响以及是否有潜力切实解决卫生系统障碍等方面的障碍进行了评分。该过程有三轮(R):(R1和R2)通过电子调查,(R3)通过面对面会议。在R1中,超过70%的参与者评分高于15分的陈述立即被优先纳入R3讨论。得分低于30%的陈述被剔除,介于两者之间的陈述在R2中重新进行调查。
29名利益相关者中有22名和17名分别对R1和R2做出了回应。14名利益相关者参加了R3。赞比亚前列腺癌的国家优先研究领域被确定为前列腺癌认知;建立负担得起的高质量诊断能力;专科癌症治疗的可负担性;支持更好地获取药物;整个诊疗路径的服务提供与协调以及人员培训。
建议的七个优先领域有助于以整体方式开展前列腺癌控制项目。期望在这一指导下,国际伙伴能够在地方可持续发展议程框架内做出贡献,以实现相关目标。