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肾自体移植的临床进展:综述

Clinical advances in kidney autotransplantation: a review.

作者信息

Lin Shengjie, Gai Jingci, Huang Shangjin, He Yingzhen, Hao Da, Luo Shuhang, Lin Yilong, Qiu Jiang, Li Jun, Wang Changxi, Wu Chenglin

机构信息

Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, China.

School of Medicine, Xiamen University, Xiamen, 361100, China.

出版信息

BMC Surg. 2025 Feb 5;25(1):54. doi: 10.1186/s12893-024-02754-z.

Abstract

Kidney autotransplantation is a surgical procedure with multiple indications and advancing technological approaches. Kidney autotransplantation is used to address complex kidney-related diseases including renal vascular lesions, ureteral diseases, tumors, loin pain-hematuria syndrome, and conditions affecting a solitary kidney or both kidneys. Renal artery lesions, including aneurysms and stenoses, often necessitate kidney autotransplantation in cases involving renal artery bifurcation or distant failure of endovascular repair. Complex ureteral lesions such as ureteral avulsions are commonly treated with kidney autotransplantation. Renal tumors, especially centrally located tumors or those involving the renal hilum, are treated using this technique while preserving renal function. It is worth emphasizing that this would be a rarely used last-resort technique in the modern era of minimally invasive nephron-sparing surgery. Kidney autotransplantation may be indicated for the rare condition of loin pain-hematuria syndrome when conservative measures fail. Additionally, individuals with solitary or bilateral kidney disease benefit from kidney autotransplantation to preserve their renal function. Traditional open-kidney autotransplantation involves renal extraction, workbench repair, and renal reimplantation. Technological advancements have introduced minimally invasive techniques including laparoscopic- and robot-assisted kidney autotransplantation, which reduce surgical trauma and recovery times. These techniques have shown promising outcomes, and robotic platforms have the potential to further reduce complications. In this study, we reviewed diverse indications and recent technological innovations in the field of kidney autotransplantation.

摘要

肾脏自体移植是一种具有多种适应证和不断发展的技术方法的外科手术。肾脏自体移植用于治疗包括肾血管病变、输尿管疾病、肿瘤、腰背痛-血尿综合征以及影响单肾或双肾的疾病等复杂的肾脏相关疾病。肾动脉病变,包括动脉瘤和狭窄,在涉及肾动脉分叉或血管内修复远处失败的情况下,通常需要进行肾脏自体移植。复杂的输尿管病变,如输尿管撕脱伤,通常采用肾脏自体移植治疗。肾肿瘤,尤其是位于中央的肿瘤或累及肾门的肿瘤,在保留肾功能的同时可使用该技术进行治疗。值得强调的是,在现代微创保留肾单位手术时代,这将是一种很少使用的最后手段技术。当保守治疗失败时,肾脏自体移植可用于治疗罕见的腰背痛-血尿综合征。此外,患有单肾或双侧肾病的个体可从肾脏自体移植中受益,以保留其肾功能。传统的开放性肾脏自体移植包括肾脏取出、手术台修复和肾脏再植入。技术进步引入了微创技术,包括腹腔镜和机器人辅助肾脏自体移植,这些技术减少了手术创伤和恢复时间。这些技术已显示出有希望的结果,并且机器人平台有可能进一步减少并发症。在本研究中,我们回顾了肾脏自体移植领域的各种适应证和最近的技术创新。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f21f/11796257/45a1ebbf09e1/12893_2024_2754_Fig1_HTML.jpg

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