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两名难治性抑郁症和广泛性焦虑症患者终纹床核和内侧前脑束深部脑刺激的长期随访

Deep Brain Stimulation in the Bed Nucleus of Stria Terminalis and Medial Forebrain Bundle in Two Patients With Treatment-Resistant Depression and Generalized Anxiety Disorder-A Long-Term Follow-Up.

作者信息

Naesström Matilda, Blomstedt Patric, Johansson Viktoria

机构信息

Department of Clinical Sciences, Psychiatry Umeå University Umeå Sweden.

Department of Clinical Sciences, Neurosciences Umeå University Umeå Sweden.

出版信息

Clin Case Rep. 2025 Feb 5;13(2):e70179. doi: 10.1002/ccr3.70179. eCollection 2025 Feb.

Abstract

This case report presents positive outcomes from deep brain stimulation (DBS) targeting the bed nucleus of the stria terminalis (BNST) in two patients with treatment-resistant depression and generalized anxiety disorder. DBS effects in the medial forebrain bundle (MFB) area were unclear. Further research into DBS's efficacy when comorbid anxiety is present is required.

摘要

本病例报告展示了针对两名难治性抑郁症和广泛性焦虑症患者的终纹床核(BNST)进行深部脑刺激(DBS)所取得的积极成果。DBS在内侧前脑束(MFB)区域的效果尚不清楚。需要进一步研究存在共病焦虑时DBS的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397c/11798865/25359bd6909b/CCR3-13-e70179-g001.jpg

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