Kim Geun-Hyo, Lim Dong-Won, Cheon Yong-Il, Shin Sung-Chan, Lee Byung-Joo, Lee Yeon-Woo
Department of Otorhinolaryngology-Head and Neck Surgery and Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
Department of Speech-Language Pathology, Kosin University, Busan, South Korea.
J Voice. 2025 Feb 7. doi: 10.1016/j.jvoice.2025.01.007.
This study aimed to evaluate the efficacy of injection laryngoplasty (IL) in improving voice quality in patients with unilateral vocal fold paralysis (UVFP), as measured by acoustic parameters.
A cohort of 177 patients with UVFP underwent preIL and postIL assessment using maximum phonation time (MPT), Acoustic Voice Quality Index (AVQI), and Acoustic Breathiness Index (ABI), in conjunction with auditory-perceptual (A-P) ratings and the Voice Handicap Index-10 (VHI-10).
Significant improvements were observed across all acoustic and perceptual measures following IL. MPT, AVQI, and ABI, as analyzed using Praat, provided comprehensive quantification of voice recovery. All three measures showed high diagnostic accuracy, with area under the curve values of ≥ 0.73. Receiver-operating characteristic analysis identified effective cutoff values for MPT, AVQI, and ABI, confirming their predictive value for voice recovery.
The findings of this study support the integration of MPT, AVQI, and ABI in clinical practice for a more precise assessment of IL outcomes in patients with UVFP. Future research should involve larger sample sizes to investigate cause-specific recovery rates and the role of postIL voice therapy.
本研究旨在评估注射喉成形术（IL）对单侧声带麻痹（UVFP）患者嗓音质量的改善效果，通过声学参数进行测量。
177例UVFP患者队列在接受IL治疗前后，使用最长发声时间（MPT）、声学嗓音质量指数（AVQI）和声学呼吸音指数（ABI）进行评估，并结合听觉感知（A-P）评分和嗓音障碍指数-10（VHI-10）。
IL治疗后，所有声学和感知指标均有显著改善。使用Praat分析的MPT、AVQI和ABI能够全面量化嗓音恢复情况。这三项指标均显示出较高的诊断准确性，曲线下面积值≥0.73。受试者工作特征分析确定了MPT、AVQI和ABI的有效临界值，证实了它们对嗓音恢复的预测价值。
本研究结果支持在临床实践中整合MPT、AVQI和ABI，以便更精确地评估UVFP患者的IL治疗效果。未来的研究应纳入更大样本量，以调查特定病因的恢复率以及IL治疗后嗓音治疗的作用。
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