Kasarla Rishabh, Beyer Maria, Cuello Sebastion, Tadepalli Pranav, Beyer Erik
Cardiothoracic Surgery, Nova Southeastern University Dr. Kiran C. Patel College of Allopathic Medicine, Davie, USA.
Cardiothoracic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, USA.
Cureus. 2025 Jan 10;17(1):e77229. doi: 10.7759/cureus.77229. eCollection 2025 Jan.
Traditional bypass methods for intracardiac thrombectomy may require direct manipulation of the heart, which carries the potential for increased stroke risk from either arrhythmias or direct dislodgement and embolization of a thrombus. Currently, there is very little research regarding the different ways to approach cardiopulmonary bypass in thrombectomy cases. This case study highlights the use of percutaneous femoral access cardiopulmonary bypass (PCPB) in the management of a large, mobile, left ventricular thrombus (LVT) in a patient with a recent stroke. In this case, a 49-year-old male with a history of an anterior wall myocardial infarction and subsequent percutaneous coronary intervention (PCI) presents now, four years later, with shortness of breath. At the time of his initial presentation, he was documented to have anterior wall akinesis and a mobile LVT. Warfarin was recommended at that time, but the patient was noncompliant. Before further workup could be completed, the patient experienced a cerebrovascular accident (CVA), but after a comprehensive workup, he was cleared for surgery two days later. The patient required surgery for apical thrombus removal and ventricular reconstruction. Following sternotomy and initiation of percutaneous cardiopulmonary bypass, an apical infarct and thrombus were identified and removed via left ventriculotomy. Purse-string sutures were placed to exclude scar tissue and restore ventricular shape, and the ventriculotomy was closed using a modified Dor procedure. The patient was successfully weaned off bypass. The patient was discharged on postoperative day 12 with normalized labs, showed excellent functional recovery, remained symptom-free at two months, and remained stable without complications at eight months. The "no touch" approach provided by percutaneous bypass minimizes the risk of complications such as a stroke, suggesting its consideration as a standard of care during left ventricular thrombectomy. This case encourages further research into PCPB as a preferable alternative to traditional bypass methods in managing left ventricular thrombi, especially in high-risk embolization scenarios.
传统的心内血栓切除术旁路方法可能需要直接对心脏进行操作,这有可能因心律失常或血栓直接脱落和栓塞而增加中风风险。目前,关于在血栓切除术病例中进行体外循环的不同方法的研究非常少。本病例研究强调了经皮股动脉入路体外循环(PCPB)在一名近期中风患者的大型、活动的左心室血栓(LVT)管理中的应用。在该病例中,一名有前壁心肌梗死病史并随后接受经皮冠状动脉介入治疗(PCI)的49岁男性,在四年后因呼吸急促前来就诊。在其初次就诊时,记录显示他有前壁运动减弱和一个活动的LVT。当时建议使用华法林,但患者未遵医嘱。在进一步检查完成之前,患者发生了脑血管意外(CVA),但经过全面检查后,两天后他被批准进行手术。患者需要进行手术以切除心尖血栓并进行心室重建。在胸骨切开术和经皮体外循环启动后,通过左心室切开术识别并切除了心尖梗死灶和血栓。放置荷包缝线以排除瘢痕组织并恢复心室形状,使用改良的Dor手术关闭心室切开术。患者成功脱离体外循环。患者在术后第12天出院,实验室检查结果正常,功能恢复良好,两个月时无症状,八个月时保持稳定无并发症。经皮旁路提供的“免接触”方法将中风等并发症的风险降至最低,表明在左心室血栓切除术中应将其视为一种护理标准。本病例鼓励进一步研究PCPB,作为在处理左心室血栓时替代传统旁路方法的更优选择,尤其是在高风险栓塞情况下。