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一款用于监测昼夜节律性食欲的智能手机应用程序的验证:在自由生活和受控环境中的随机交叉试验。

Validation of a Smartphone Application for Monitoring Circadian Appetite: A Randomized Crossover Trial in Free-Living and Controlled Settings.

作者信息

Tsameret Shani, Froy Oren

机构信息

Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.

出版信息

Nutrients. 2025 Jan 22;17(3):384. doi: 10.3390/nu17030384.

Abstract

BACKGROUND/OBJECTIVES: Appetite is affected by the circadian clock and exhibits diurnal variations. Nevertheless, accurately measuring subjective appetite throughout the day in a free-living setting poses a challenge. This study presents the validation of a novel smartphone application designed to capture, process and analyze circadian appetite fluctuations in a free-living setting.

METHODS

Twenty-four healthy participants (ages 38.34 ± 3.2 years) completed this randomized crossover study. Participants completed subjective appetite questionnaires every 30 min in a free-living environment, starting from waking hours until bedtime, using visual analog scale (VAS) via the pen and paper (PP) method and the new smartphone application (App). In addition, on two experimental days, separated by a week of washout, participants were provided either a high-energy breakfast (850 kcal) or a low-energy breakfast (250 kcal). Participants completed the appetite questionnaires using both methods every 30 min for 4 h, followed by an ad libitum lunch.

RESULTS

The high-energy breakfast led to significantly increased fullness sensation and decreased hunger, desire to eat, prospective consumption, and appetite score compared with the low-energy breakfast. There was no significant difference between the methods (PP and App) in all measured parameters under both the free-living environment and the controlled environment. Additionally, Bland-Altman analysis revealed a high degree of agreement between the PP and App methods. Moreover, most participants rated the App as the preferred method regardless of age.

CONCLUSIONS

Our findings show that the new smartphone application is a valid, reliable tool for measuring subjective appetite, suitable for use in chrononutritional studies conducted in a free-living environment and controlled settings.

摘要

背景/目的:食欲受生物钟影响并呈现昼夜变化。然而,在自由生活环境中准确测量一整天的主观食欲是一项挑战。本研究展示了一款新型智能手机应用程序的验证情况,该应用旨在捕捉、处理和分析自由生活环境中的昼夜食欲波动。

方法

24名健康参与者(年龄38.34±3.2岁)完成了这项随机交叉研究。参与者在自由生活环境中从醒来至就寝期间,每隔30分钟通过纸笔(PP)方法和新的智能手机应用程序(应用程序)使用视觉模拟量表(VAS)完成主观食欲问卷。此外,在两个实验日(中间间隔一周洗脱期),参与者分别被给予高能量早餐(850千卡)或低能量早餐(250千卡)。参与者使用两种方法每隔30分钟完成4小时的食欲问卷,随后进行随意午餐。

结果

与低能量早餐相比,高能量早餐导致饱腹感显著增加,饥饿感、进食欲望、预期摄入量和食欲评分降低。在自由生活环境和受控环境下,两种方法(PP和应用程序)在所有测量参数上均无显著差异。此外,Bland - Altman分析显示PP和应用程序方法之间具有高度一致性。而且,无论年龄如何,大多数参与者将应用程序评为首选方法。

结论

我们的研究结果表明,这款新的智能手机应用程序是测量主观食欲的有效、可靠工具,适用于在自由生活环境和受控环境中进行的时间营养学研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f27/11820149/461ad59480ba/nutrients-17-00384-g003.jpg

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