Suppr超能文献

饮食习惯、肥胖与减肥手术:影响与干预综述

Dietary Habits, Obesity, and Bariatric Surgery: A Review of Impact and Interventions.

作者信息

Maxim Mădălina, Soroceanu Radu Petru, Vlăsceanu Vlad Ionuț, Platon Răzvan Liviu, Toader Mihaela, Miler Ancuța Andreea, Onofriescu Alina, Abdulan Irina Mihaela, Ciuntu Bogdan-Mihnea, Balan Gheorghe, Trofin Felicia, Timofte Daniel Vasile

机构信息

"Grigore T. Popa" University of Medicine and Pharmacy, Faculty of Medicine, Str. Universitatii, No 16, 700115 Iasi, Romania.

Department of General Surgery, County Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania.

出版信息

Nutrients. 2025 Jan 28;17(3):474. doi: 10.3390/nu17030474.

Abstract

Eating behavior encompasses the psychological, physiological, and environmental factors influencing food intake. Dysregulation in eating behavior, such as emotional eating, binge eating, or loss of satiety signals, contributes to excessive caloric intake and weight gain. These behaviors are often linked to hormonal imbalances, stress, or genetic predisposition. Obesity is a chronic, multifactorial disease characterized by excessive body fat accumulation, with a body mass index (BMI) ≥ 30 kg/m often used for diagnosis. It is associated with significant morbidity, including type 2 diabetes, cardiovascular disease, and obstructive sleep apnea. Pathophysiological mechanisms underlying obesity include insulin resistance, leptin dysregulation, and altered gut microbiota, which perpetuate metabolic derangements. Lifestyle interventions remain first-line treatment, but sustained weight loss is challenging for many patients. Bariatric surgery is a therapeutic option for individuals with severe obesity (BMI ≥ 40 kg/m or ≥35 kg/m with comorbidities) who have failed conservative management. Procedures such as Roux-en-Y gastric bypass and sleeve gastrectomy alter gastrointestinal anatomy, promoting weight loss through restriction, malabsorption, and hormonal modulation (e.g., increased GLP-1 secretion). Bariatric surgery improves obesity-related comorbidities and enhances quality of life. However, it requires lifelong medical follow-up to address potential nutritional deficiencies and ensure sustainable outcomes.

摘要

饮食行为包括影响食物摄入的心理、生理和环境因素。饮食行为失调,如情绪化进食、暴饮暴食或饱腹感信号丧失,会导致热量摄入过多和体重增加。这些行为通常与激素失衡、压力或遗传易感性有关。肥胖是一种慢性多因素疾病,其特征是身体脂肪过度堆积,常使用体重指数(BMI)≥30kg/m²进行诊断。它与严重的发病率相关,包括2型糖尿病、心血管疾病和阻塞性睡眠呼吸暂停。肥胖的病理生理机制包括胰岛素抵抗、瘦素失调和肠道微生物群改变,这些会使代谢紊乱持续存在。生活方式干预仍然是一线治疗方法,但对许多患者来说,持续减重具有挑战性。减重手术是针对重度肥胖(BMI≥40kg/m²或BMI≥35kg/m²且伴有合并症)且保守治疗失败的个体的一种治疗选择。诸如Roux-en-Y胃旁路术和袖状胃切除术等手术会改变胃肠道解剖结构,通过限制、吸收不良和激素调节(如增加胰高血糖素样肽-1分泌)来促进体重减轻。减重手术可改善与肥胖相关的合并症并提高生活质量。然而,它需要终身医学随访以解决潜在的营养缺乏问题并确保可持续的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/301d/11820207/e6b28a6ee4f6/nutrients-17-00474-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验