生物转化产率必须考虑所有碳：复杂培养基带来的潜在偏差。
Bioconversion yields must account for all carbon: hidden biases from complex media.
作者信息
Yook Sangdo, Alper Hal S
机构信息
McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.
McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA; Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, USA.
出版信息
Trends Biotechnol. 2025 Feb 17. doi: 10.1016/j.tibtech.2025.01.010.
Yield ratio is a critical parameter for quantifying bioprocess conversion efficiency. However, unquantified carbon in complex media formulations complicates yield calculations. We highlight the biases introduced by improperly neglecting all carbon-containing molecules. We recommend that yields be reported by accounting for all carbon and that media formulations are always stated.
产率比是量化生物过程转化效率的关键参数。然而，复杂培养基配方中未量化的碳会使产率计算变得复杂。我们强调了不当忽略所有含碳分子所引入的偏差。我们建议通过考虑所有碳来报告产率，并始终说明培养基配方。
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