Huang Chung-Tsui, Chen Chao-Yi, Liang Yao-Jen
Department of Internal Medicine, Division of Gastroenterology and Hepatology, Far Eastern Memorial Hospital, New Taipei City 220, Taiwan.
Graduate Institute of Applied Science and Engineering, Fu-Jen Catholic University, New Taipei City 242, Taiwan.
Life (Basel). 2025 Feb 14;15(2):300. doi: 10.3390/life15020300.
Copper contamination in coastal water environments poses a significant health risk, and traditional treatments for copper intoxication include gastric lavage, chelation, and hemodialysis. Recent research suggests that probiotics may help mitigate heavy metal toxicity by promoting biosorption in the intestinal tract. To explore this potential, we investigated the protective effects of () against copper-induced toxicity in rats. After eight weeks of exposure, rats receiving both copper and exhibited significant improvements in renal function, lipid profiles, antioxidant enzyme activity, and histological markers compared to the copper-only group. However, liver function remained largely unchanged, suggesting a more pronounced protective effect on renal health. These findings highlight the potential of as a supportive intervention for mitigating the adverse effects of copper intoxication.
沿海水环境中的铜污染构成了重大的健康风险,传统的铜中毒治疗方法包括洗胃、螯合和血液透析。最近的研究表明,益生菌可能通过促进肠道中的生物吸附来帮助减轻重金属毒性。为了探索这种潜力,我们研究了()对大鼠铜诱导毒性的保护作用。暴露八周后,与仅接受铜的组相比,同时接受铜和()的大鼠在肾功能、脂质谱、抗氧化酶活性和组织学指标方面有显著改善。然而,肝功能基本保持不变,这表明对肾脏健康有更明显的保护作用。这些发现凸显了()作为减轻铜中毒不良影响的支持性干预措施的潜力。