Fan Yufei, Chen Xi, Shan Tiantian, Wang Nanxi, Han Qi, Ren Biao, Cheng Lei
State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
J Oral Microbiol. 2025 Feb 25;17(1):2469896. doi: 10.1080/20002297.2025.2469896. eCollection 2025.
infection affects approximately 50% of the global population. The predominant route of transmission is through the oral pathway, making the oral cavity highly significant in its infection. This review focuses on the relationship between and oral diseases, the influence of infection on the oral microbiota, and the potential mechanisms involving certain oral pathogens.
To identify relevant studies, we conducted searches in PubMed, Google Scholar using keywords such as "," "oral diseases, " "oral microorganisms, " without any date restrictions. The retrieved publications were subject to a review.
infection is positively correlated with the occurrence of various oral diseases, such as dental caries, periodontitis, and oral lichen planus. may affect the oral microbiota through various mechanisms, and there exists an interactive relationship between and oral bacteria, including , , and .
infection has a close relationship with certain oral diseases. modulates oral microflora diversity and structure, while eradication therapy and medications have varying impacts on oral microbiota.
感染影响着全球约50%的人口。主要传播途径是通过口腔途径,这使得口腔在感染方面具有高度重要性。本综述重点关注[感染因素]与口腔疾病之间的关系、[感染因素]感染对口腔微生物群的影响以及涉及某些口腔病原体的潜在机制。
为了确定相关研究,我们在PubMed、谷歌学术上使用诸如“[感染因素]”“口腔疾病”“口腔微生物”等关键词进行检索,没有任何日期限制。对检索到的出版物进行了综述。
[感染因素]感染与各种口腔疾病的发生呈正相关,如龋齿、牙周炎和口腔扁平苔藓。[感染因素]可能通过多种机制影响口腔微生物群,并且[感染因素]与口腔细菌之间存在相互作用关系,包括[具体细菌种类1]、[具体细菌种类2]和[具体细菌种类3]。
[感染因素]感染与某些口腔疾病密切相关。[感染因素]调节口腔微生物群的多样性和结构,而根除治疗和药物对口腔微生物群有不同的影响。