Tariq Javeria, Ansari Asefa Shariq, Mistry Akbar, Abbas Qalab, Ahmad Waris, Amanullah Muneer, Malik Mahim, Mohsin Shazia
Division of cardiothoracic sciences, Sindh institute of urology and transplantation, Karachi, Pakistan.
Clinical Research Cardiology Department, Tabba Heart Institute, Karachi, Pakistan.
Pediatr Cardiol. 2025 Feb 27. doi: 10.1007/s00246-025-03813-9.
Tetralogy of Fallot (TOF) is a common congenital heart defect with a traditionally high reintervention rate of post-surgical correction. The Residual Lesion Score (RLS) is a tool used to evaluate the quality of surgical outcomes by assessing postoperative echocardiography findings and the need for unplanned reinterventions. The study assesses the association between the Residual Lesion Score (RLS) and early and midterm outcomes, including reintervention rates, in patients undergoing valve-sparing TOF repair at a tertiary care center in a low- and middle-income country (LMIC). We conducted a retrospective analysis of 62 patients who underwent valve-sparing TOF repair between January 2017 and December 2019 at Aga Khan University, Pakistan. The RLS was calculated based on postoperative echocardiograms and unplanned surgical or catheter-based reinterventions. Patients were categorized into RLS 1 (trivial or no residual lesions), RLS 2 (minor residual lesions), and RLS 3 (major residual lesions or reinterventions before discharge). Two (3.2%) patients lacked postoperative echocardiography, were assigned an RLS score of 5, and excluded from further analysis. Of the 60 patients, 13 (21%) had an RLS of 3, indicating major residual lesions, and 29 (48.3%) had an RLS of 2, indicating minor residual lesions. Early reinterventions were required in 11.7% of patients. Patients with RLS 3 had a significantly higher reintervention rate compared to those with RLS 2 (p = 0.003) reintervention and longer hospital stay (p-value = 0.3). Implementing RLS can help optimize postoperative management and patient outcomes by identifying patients at higher risk of early reintervention.
法洛四联症(TOF)是一种常见的先天性心脏缺陷,传统上手术矫正后的再次干预率较高。残余病变评分(RLS)是一种用于通过评估术后超声心动图结果和计划外再次干预的必要性来评估手术结果质量的工具。本研究评估了在一个低收入和中等收入国家(LMIC)的三级医疗中心接受保留瓣膜TOF修复的患者中,残余病变评分(RLS)与早期和中期结果(包括再次干预率)之间的关联。我们对2017年1月至2019年12月在巴基斯坦阿迦汗大学接受保留瓣膜TOF修复的62例患者进行了回顾性分析。RLS是根据术后超声心动图以及计划外的手术或基于导管的再次干预来计算的。患者被分为RLS 1(轻微或无残余病变)、RLS 2(轻度残余病变)和RLS 3(主要残余病变或出院前再次干预)。两名(3.2%)患者缺乏术后超声心动图检查,被赋予RLS评分为5,并被排除在进一步分析之外。在这60例患者中,13例(21%)的RLS为3,表明存在主要残余病变,29例(48.3%)的RLS为2,表明存在轻度残余病变。11.7%的患者需要早期再次干预。与RLS 2的患者相比,RLS 3的患者再次干预率显著更高(p = 0.003),住院时间更长(p值 = 0.3)。实施RLS可以通过识别早期再次干预风险较高的患者来帮助优化术后管理和患者预后。