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髓芯减压术后转为髋关节置换术的发生率。

The incidence of conversion to hip arthroplasty after core decompression.

作者信息

Tang Hao-Che, Ling Daphne I, Hsu Shu-Han, Chuang Chieh-An, Hsu Kai-Lan, Ku Li-Jung E

机构信息

Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan.

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

出版信息

Bone Joint J. 2025 Mar 1;107-B(3):308-313. doi: 10.1302/0301-620X.107B3.BJJ-2024-0815.R1.

Abstract

AIMS

Core decompression is a commonly performed procedure to treat osteonecrosis of the femoral head (ONFH) prior to femoral head collapse. The aim of the study was to identify the incidence of hip arthroplasty after core decompression and the potential risk factors for conversion through a nationwide population-based study.

METHODS

Patients who received core decompression for ONFH between 1 January 2009 and 31 December 2018 and were followed up until 31 December 2019 (mean 33 months (0.2 to 132)) were retrieved from Taiwan's National Health Insurance claims database. A total of 2,918 patients were identified and included in the study. The mean age at the time of core decompression was 46 years (SD 12.5), with a male-to-female ratio of 7:3. The first total hip arthroplasty or hip hemiarthroplasty after the index core decompression was considered as the outcome of conversion to hip arthroplasty. For the analysis of conversion risk, patients' demographic characteristics, economic status, comorbidities, and data on the type of hospital and surgeons' experience were included.

RESULTS

Overall, 20.05% of patients received a hip arthroplasty within six months following core decompression, with the incidence rising to 60.6% by five years and 66.4% by ten years. Multivariable analysis revealed that patients aged over 40 years (HR 1.18 (95% CI 1.07 to 1.30); p = 0.002), who had a history of alcohol abuse (HR 1.57 (95% CI 1.22 to 2.02); p < 0.001), and had their procedures performed at district-level hospitals (HR 1.13 (95% CI 1.00 to 1.26; p = 0.044), were at increased risk of conversion to hip arthroplasty following core decompression.

CONCLUSION

The five- and ten-year cumulative incidence of conversion to hip arthroplasty after core decompression was 60.6% and 66.4%, respectively. Significant risk factors for conversion to hip arthroplasty included age over 40 years, history of alcohol abuse, and procedures performed at district hospitals.

摘要

目的

核心减压是在股骨头塌陷前治疗股骨头坏死(ONFH)的常用手术。本研究的目的是通过一项基于全国人群的研究,确定核心减压后髋关节置换术的发生率以及转换的潜在风险因素。

方法

从台湾国民健康保险理赔数据库中检索2009年1月1日至2018年12月31日期间接受ONFH核心减压治疗并随访至2019年12月31日(平均33个月(0.2至132个月))的患者。共识别出2918例患者并纳入研究。核心减压时的平均年龄为46岁(标准差12.5),男女比例为7:3。首次核心减压后的初次全髋关节置换术或半髋关节置换术被视为转换为髋关节置换术的结果。为了分析转换风险,纳入了患者的人口统计学特征、经济状况、合并症以及医院类型和外科医生经验的数据。

结果

总体而言,20.05%的患者在核心减压后6个月内接受了髋关节置换术,5年时发生率升至60.6%,10年时升至66.4%。多变量分析显示,年龄超过40岁的患者(风险比1.18(95%置信区间1.07至1.30);p = 0.002)、有酗酒史的患者(风险比1.57(95%置信区间1.22至2.02);p < 0.001)以及在区级医院接受手术的患者(风险比1.13(95%置信区间1.00至1.26;p = 0.044)),在核心减压后转换为髋关节置换术的风险增加。

结论

核心减压后转换为髋关节置换术的5年和10年累积发生率分别为60.6%和66.4%。转换为髋关节置换术的显著风险因素包括年龄超过40岁、酗酒史以及在区级医院进行的手术。

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