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中国台州某三级医院关于新冠病毒感染后前列腺穿刺活检术后并发症的前瞻性临床研究

A Prospective Clinical Study on Postoperative Complications of Prostate Biopsy Following COVID-19 Infection at a Tertiary Hospital in Taizhou, China.

作者信息

Zhang Dong-Sheng, Chen Yu-Yi, Zhu Jia-Jia, Wang Rong, Sun Liang-Xue

机构信息

Department of General Surgery, The First People's Hospital of Jiande, Jiande, Zhejiang, China.

Department of Urology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.

出版信息

Can J Infect Dis Med Microbiol. 2025 Feb 24;2025:6451174. doi: 10.1155/cjid/6451174. eCollection 2025.

Abstract

Postoperative complications in individuals with a prior history of COVID-19 infection have been insufficiently investigated. This study is conducted to explore the postoperative complications of prostate biopsy in patients following a COVID-19 infection. Data from individuals who underwent a prostate biopsy at a tertiary hospital in Taizhou city from 1 February to 15 November 2023 were collected, including a history of COVID-19 infection, a history of chronic disease, and postoperative complications of prostate biopsy. A total of 526 participants were enrolled in the study, with 325 individuals having a prior history of COVID-19 infection. The interval between infection and prostate biopsy was 29.25 ± 12.75 weeks, with a fluctuation range from 0.71 to 87.57 weeks. In individuals with a history of COVID-19 infection, 72 were asymptomatic, 110 experienced respiratory symptoms, and 145 had fever. In total, 198 patients reported postoperative complications, which showed no statistically significant difference with a history of COVID-19 infection (=0.217). The top three reported postoperative complications were hematuria, perineal pain, and urinary retention, which tended not to be related to a history of COVID-19 infection (=0.448, =0.991, and =0.277, respectively). The incidence of postoperative complications of prostate biopsy in post-COVID-19 patients, who currently have no symptoms of COVID-19 infection, was comparable to patients with no history of COVID-19 infection. In clinical practice, for males with a history of controlled COVID-19 infection, the risk of postoperative complications from prostate biopsy should not be a major concern.

摘要

既往有新冠病毒感染史个体的术后并发症尚未得到充分研究。本研究旨在探讨新冠病毒感染患者前列腺活检后的术后并发症。收集了2023年2月1日至11月15日在台州市一家三级医院接受前列腺活检的个体的数据,包括新冠病毒感染史、慢性病病史以及前列腺活检的术后并发症。共有526名参与者纳入本研究,其中325人有新冠病毒感染史。感染与前列腺活检之间的间隔为29.25±12.75周,波动范围为0.71至87.57周。在有新冠病毒感染史的个体中,72人无症状,110人有呼吸道症状,145人发热。共有198例患者报告了术后并发症,与新冠病毒感染史无统计学显著差异(P=0.217)。报告的前三大术后并发症是血尿、会阴部疼痛和尿潴留,这些并发症往往与新冠病毒感染史无关(分别为P=0.448、P=0.991和P=0.277)。目前无新冠病毒感染症状的新冠病毒感染后患者前列腺活检术后并发症的发生率与无新冠病毒感染史的患者相当。在临床实践中,对于有新冠病毒感染史且病情已得到控制的男性,前列腺活检术后并发症的风险不应成为主要担忧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d8c/11876521/32a3d610330a/CJIDMM2025-6451174.001.jpg

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