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通过紧急医疗调度中心减少与中风疑似病例相关的时间延迟并提高再灌注适宜性:一项基于登记处的观察性研究。

Reducing time delays and enhancing reperfusion eligibility related to stroke suspicion by the Emergency Medical Dispatch Centre: a registry-based observational study.

作者信息

Leto Nedim, Farbu Elisabeth, Barach Paul, Busch Michael, Lund Helene, Bjørshol Conrad Arnfinn, Kurz Martin, Fromm Annette, Østerås Øyvind, Hagen Linn Therese, Lindner Thomas Werner

机构信息

Department of Clinical Medicine, University of Bergen, Bergen, Norway

Regional Centre for Emergency Medical Research and Development in Western Norway (RAKOS), Stavanger, Norway.

出版信息

Emerg Med J. 2025 Aug 19;42(9):599-605. doi: 10.1136/emermed-2024-214294.

Abstract

BACKGROUND AND AIMS

Research on the importance of the Emergency Medical Dispatch Centre (EMDC) role in reducing the time delays for patients with acute ischaemic stroke (AIS) is limited. This study aimed to analyse how Norwegian EMDCs' accurate suspicions can impact the clinical care times in this patient group.

METHODS

We collected clinical care time metrics and acute reperfusion treatment data from the Norwegian Stroke Registry on patients with AIS in Western Norway who were evaluated by the EMDC and had an ambulance dispatched in 2021. In case a stroke was suspected by the EMDC, the dispatcher communicated their diagnosis suspicions to the ambulance personnel. Outcomes of interest were reperfusion treatment for AIS, prehospital and in-hospital time-to-treatment delays, and patient outcomes.

RESULTS

Of the 1106 patients with AIS in our region, 771 (70 %) fulfilled the inclusion criteria. The EMDC suspected a stroke in 481 cases (62 %). Patients with suspected stroke experienced lower ambulance on-scene times (11 min vs 15 min; p=0.001), Emergency Medical Service prehospital times (40 min vs 49 min; p=0.021) and door-to-needle times (23 min vs 31 min; p=0.023). The EMDC stroke suspicion was associated with increased thrombolysis rates (OR 2.42 (95% CI 1.72 to 3.40)) after adjusting for age, sex, risk factors and functional status prior to the stroke event. The door-to-groin puncture times were lower for patients with a stroke suspicion who received endovascular treatment (65 min vs 85 min; p=0.004). No differences in the National Institutes of Health Stroke Scale score at the initial hospital arrival (4 vs 4; p=0.42) or in 90-day functional independence outcomes (rate of modified Rankin Scale score 0-2; 240 (61%) vs 160 (66%); p=0.24) were observed.

CONCLUSIONS

Accurate EMDC recognition of stroke suspicion alerts to ambulances were associated with a reduction in time until treatment and increased intravenous thrombolysis rates. A significant proportion of patients who had a stroke were not identified by the dispatcher. Improving dispatcher stroke assessment training, tools and knowledge may reduce time delays, thus improving patient outcomes.

摘要

背景与目的

关于急诊医疗调度中心(EMDC)在减少急性缺血性卒中(AIS)患者治疗时间延迟方面的重要性的研究有限。本研究旨在分析挪威EMDC的准确怀疑如何影响该患者群体的临床护理时间。

方法

我们从挪威卒中登记处收集了2021年由EMDC评估并派遣救护车的挪威西部AIS患者的临床护理时间指标和急性再灌注治疗数据。如果EMDC怀疑是卒中,调度员会将他们的诊断怀疑告知救护人员。感兴趣的结果是AIS的再灌注治疗、院前和院内治疗时间延迟以及患者结局。

结果

在我们地区的1106例AIS患者中,771例(70%)符合纳入标准。EMDC怀疑卒中481例(62%)。疑似卒中患者的救护车现场时间(11分钟对15分钟;p=0.001)、紧急医疗服务院前时间(40分钟对49分钟;p=0.021)和门到针时间(23分钟对31分钟;p=0.023)较低。在调整年龄、性别、危险因素和卒中事件前的功能状态后,EMDC对卒中的怀疑与溶栓率增加相关(比值比2.42(95%可信区间1.72至3.40))。接受血管内治疗的疑似卒中患者的门到股动脉穿刺时间较低(65分钟对85分钟;p=0.004)。在初始入院时的美国国立卫生研究院卒中量表评分(4对4;p=0.42)或90天功能独立结局(改良Rankin量表评分0 - 2的比例;240例(61%)对160例(66%);p=0.24)方面未观察到差异。

结论

EMDC对卒中怀疑的准确识别并向救护车发出警报与治疗前时间的减少和静脉溶栓率的增加相关。很大一部分卒中患者未被调度员识别。改善调度员卒中评估培训、工具和知识可能会减少时间延迟,从而改善患者结局。

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