肝病对醋丁洛尔和双醋洛尔药代动力学无影响：一项单剂量研究。
Lack of effect of liver disease on the pharmacokinetics of acebutolol and diacetolol: a single dose study.
作者信息
Zaman R, Jack D B, Wilkins M R, Kendall M J
出版信息
Biopharm Drug Dispos. 1985 Apr-Jun;6(2):131-7. doi: 10.1002/bdd.2510060204.
PMID:4005393
Abstract
The pharmacokinetics of acebutolol and its major metabolite, diacetolol, following a single 400 mg oral dose, were investigated in patients with liver disease. No significant differences were found in any of the parameters measured.
摘要
在肝病患者中研究了单次口服400毫克醋丁洛尔及其主要代谢产物双醋洛尔后的药代动力学。在所测量的任何参数中均未发现显著差异。
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