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德国成年人中的性侵犯经历、抑郁与大量物质使用:一项探索性中介分析

Sexual assault experience, depression, and heavy substance use among German adults: an exploratory mediation analysis.

作者信息

Belau Matthias Hans, Wiessner Christian, Sehner Susanne, Dekker Arne, Briken Peer

机构信息

Institute of Medical Biometry and Epidemiology, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.

Institute of Sex Research, Sexual Medicine, and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

出版信息

BMC Public Health. 2025 Mar 10;25(1):935. doi: 10.1186/s12889-025-22117-4.

Abstract

BACKGROUND

The experience of sexual assault may be associated with numerous adverse outcomes, including depressive disorders and heavy substance use. We aimed to examine the relationship between heavy substance use and depression in victims of sexual assault.

METHODS

We used nationally representative data from the German Health and Sexuality Survey (GeSiD) with N = 4,955 women and men aged 18-75 years. We assessed (i) the potential effect of sexual assault experience on depression mediated through hazardous alcohol, heavy tobacco, and frequent cannabis use and (ii) sexual assault experience on heavy substance use mediated through depression using logistic regression analysis to estimate proportion mediated (PM).

RESULTS

We found some evidence of mediation between sexual assault as a lifetime event and depression by heavy tobacco use (PM = 1.6%) and frequent cannabis use (PM = 14.7%) among women. We also observed mediation by hazardous alcohol use (PM = 35.5%) and heavy tobacco use (PM = 48.6%) among men who experienced childhood sexual assault. Focusing on depression as a potential mediator, we found some evidence of mediation between sexual assault as a lifetime event and heavy tobacco use among women (PM = 17.6%) and men (PM = 13.3%), and between sexual assault as a lifetime event and frequent cannabis use (PM = 26.9%) among women.

CONCLUSIONS

Our findings suggest that public health specialists, clinicians, and therapists should develop early interventions to prevent addiction and the development of depression after experiencing sexual assault.

摘要

背景

性侵犯经历可能与众多不良后果相关,包括抑郁症和大量使用毒品。我们旨在研究性侵犯受害者中大量使用毒品与抑郁症之间的关系。

方法

我们使用了来自德国健康与性调查(GeSiD)的具有全国代表性的数据,样本包括4955名年龄在18 - 75岁之间的女性和男性。我们评估了:(i)性侵犯经历通过危险饮酒、大量吸烟和频繁使用大麻对抑郁症产生的潜在影响;(ii)性侵犯经历通过抑郁症对大量使用毒品产生的影响,使用逻辑回归分析来估计中介比例(PM)。

结果

我们发现一些证据表明,在女性中,终身性侵犯经历与抑郁症之间存在由大量吸烟(PM = 1.6%)和频繁使用大麻(PM = 14.7%)介导的中介效应。我们还观察到,在经历过儿童期性侵犯的男性中,危险饮酒(PM = 35.5%)和大量吸烟(PM = 48.6%)存在中介效应。将抑郁症作为潜在中介因素来看,我们发现一些证据表明,在女性(PM = 17.6%)和男性(PM = 13.3%)中,终身性侵犯经历与大量吸烟之间存在中介效应,在女性中,终身性侵犯经历与频繁使用大麻之间也存在中介效应(PM = 26.9%)。

结论

我们的研究结果表明,公共卫生专家、临床医生和治疗师应制定早期干预措施,以预防性侵犯后成瘾和抑郁症的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1e2/11892163/cc3831964c1b/12889_2025_22117_Fig1_HTML.jpg

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