来自参与MyPeBS研究的6个国家的专业人员和医疗服务提供者对基于风险的乳腺癌筛查的可接受性。

Acceptability of risk-based breast cancer screening among professionals and healthcare providers from 6 countries contributing to the MyPeBS study.

作者信息

Roux Alexandra, Hervouet Lucile, Stefano Francesca Di, French David P, Giordano Livia, Ritchie David, Bugat Marie-Eve Rougé, Keatley Debbie, Cholerton Rachel, McWilliams Lorna, Rossi Paolo Giorgi, Balleyguier Corinne, Guindy Michal, Gilbert Fiona J, Burrion Jean-Benoit, Roman Marta, Vissac-Sabatier Cécile, Couch Daniel, Delaloge Suzette, Montgolfier Sandrine de

机构信息

Aix Marseille Univ, Inserm, IRD, ISSPAM, SESSTIM, Marseille, France.

IRIS Institut de recherche interdisciplinaire sur les enjeux sociaux (UMR 8156 CNRS - 997 INSERM - EHESS - UPSN), Campus Condorcet, Aubervilliers, France.

出版信息

BMC Cancer. 2025 Mar 15;25(1):483. doi: 10.1186/s12885-025-13848-z.

DOI:10.1186/s12885-025-13848-z

PMID:40089664

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11910845/

Abstract

BACKGROUND

To evaluate the acceptability of a risk-based breast cancer screening (BCS) strategy among professionals involved in MyPeBS study in 6 countries.

METHODS

After qualitative interviews, a questionnaire was built with a Delphi method: to evaluate professionals' basic understanding, satisfaction and reactions to each stage of the trial, opinions on BCS and its future. The questionnaire was distributed by emailing 698 investigators, who forwarded it to all categories of professionals involved in trial recruitment (physicians, medical secretaries, nurses, and mammography technicians). Descriptive statistics were used to summarize views on acceptability.

RESULTS

Among the 198 respondents, most declared being at ease with the trial design and the concept of breast cancer risk estimation. They were mostly comfortable explaining the different trial steps, communicating risk estimation, and answering women's questions. Some professionals were not comfortable explaining high (7.1%) and low-risk categories (9%) and did not feel sufficiently trained (26.5%). Although professionals were mostly confident about risk-based approaches and the potential of this to improve breast cancer screening (93.5%), 58% called for further validation of the risk-models to predict risk before implementation in population-based programs. They expressed concerns about the complexity of this screening strategy, stressing the need to properly inform the public and to train professionals in delivering risk assessment.

CONCLUSION

This first study assessing the perspectives of professionals delivering risk-based BCS. As professional acceptability is key for successful implementation, training for all professionals and tools to help them communicate risk to women will be necessary to develop risk assessment in BCS.

TRIAL REGISTRATION

Study sponsor: Unicancer. My personalised breast screening (MyPeBS).

CLINICALTRIALS

gov (2018) available at https://www.

CLINICALTRIALS

gov/ct2/show/NCT03672331 .

摘要

背景

评估基于风险的乳腺癌筛查（BCS）策略在6个国家参与MyPeBS研究的专业人员中的可接受性。

方法

在定性访谈之后，采用德尔菲法构建了一份问卷：以评估专业人员对试验各阶段的基本理解、满意度和反应，对BCS及其未来的看法。通过向698名研究者发送电子邮件来分发问卷，这些研究者将问卷转发给参与试验招募的各类专业人员（医生、医学秘书、护士和乳腺摄影技师）。使用描述性统计来总结关于可接受性的观点。

结果

在198名受访者中，大多数人表示对试验设计和乳腺癌风险评估概念感到放心。他们大多能够轻松解释不同的试验步骤、传达风险评估结果并回答女性的问题。一些专业人员对解释高风险（7.1%）和低风险类别（9%）感到不自在，并且觉得没有得到充分的培训（26.5%）。尽管专业人员大多对基于风险的方法及其改善乳腺癌筛查的潜力充满信心（93.5%），但58%的人呼吁在基于人群的项目中实施之前对预测风险的风险模型进行进一步验证。他们对这种筛查策略的复杂性表示担忧，强调需要适当地向公众提供信息，并培训专业人员进行风险评估。