Litjens Elisabeth J R, Dani Melanie, Verberne Wouter R, Van Den Noortgate Nele J, Joosten Hanneke M H, Brys Astrid D H
Department of Internal Medicine, Division of Nephrology, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.
Department of Geriatrics, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London W2 1NY, UK.
J Clin Med. 2025 Mar 5;14(5):1749. doi: 10.3390/jcm14051749.
As the global population ages, so too does the prevalence of older people with chronic kidney disease (CKD). Helping people age well with CKD and supporting older people with end-stage kidney disease (ESKD) to make personalized decisions regarding kidney replacement therapy (KRT) or conservative care (CC) are an essential component of care. However, these factors are relatively underreported in both the fields of nephrology and geriatric medicine, and prospective, randomized evidence is lacking. This narrative review article, authored by both nephrologists and geriatricians, discusses specific geriatric issues that arise in older people with CKD and why they matter. The available evidence for KRT or CC in older people with frailty is outlined. The importance of performing a comprehensive geriatric assessment, or a modified nephrogeriatric assessment, to ensure a systematic evaluation of the person's medical problems and life needs, goals, and values is described. We consider different models of nephrogeriatric care and how they may be implemented. Kidney supportive care-addressing an individual's symptoms and overall well-being alongside the more traditional nephrological principles of preventing disease progression and optimizing risk-is highlighted throughout the article. We outline ways of identifying the later stages of a person's disease journey, when transition to palliative care is indicated, and elaborate methods of preparing patients for this through multidisciplinary advance care planning. Finally, we discuss practice and systems for nephrogeriatric care in five different European countries and consider future directions, challenges, and highlights in this rapidly evolving, increasingly relevant field.
随着全球人口老龄化,患有慢性肾脏病(CKD)的老年人患病率也在上升。帮助患有CKD的人健康老龄化,并支持患有终末期肾病(ESKD)的老年人就肾脏替代治疗(KRT)或保守治疗(CC)做出个性化决策,是护理的重要组成部分。然而,这些因素在肾脏病学和老年医学领域的报道都相对较少,且缺乏前瞻性随机证据。这篇叙述性综述文章由肾脏病学家和老年病学家共同撰写,讨论了患有CKD的老年人中出现的特定老年问题及其重要性。概述了针对体弱老年人进行KRT或CC的现有证据。描述了进行全面老年评估或改良的肾老年评估以确保系统评估个人医疗问题、生活需求、目标和价值观的重要性。我们考虑了不同的肾老年护理模式及其实施方式。文章通篇强调了肾脏支持性护理——在预防疾病进展和优化风险等更传统的肾脏病学原则的同时,解决个人症状和整体幸福感。我们概述了确定疾病晚期阶段(即需要过渡到姑息治疗)的方法,并详细阐述了通过多学科预先护理计划让患者为此做好准备的方法。最后,我们讨论了五个不同欧洲国家的肾老年护理实践和体系,并考虑了这个快速发展、日益相关领域的未来方向、挑战和重点。