Kim Min-Kyo, Koh Su-Han, Kim Tae-Kyu
Department of Physical Education, Pusan National University, 2 Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241, Republic of Korea.
J Clin Med. 2025 Mar 6;14(5):1777. doi: 10.3390/jcm14051777.
This study explored the impact of a 12-week walking and barre exercise program on depression levels (CES-D), stress hormones (dopamine, epinephrine, norepinephrine, cortisol, serotonin), high-sensitivity C-reactive protein (hs-CRP), and immunoglobulins (IgA, IgG, IgM) in women aged 65 and above. Twenty-seven participants were divided into a walking exercise group (WG), barre exercise group (BG) and control group (CG), each comprising nine individuals. Sessions lasted 50 min, thrice weekly, with intensity progressing every 4 weeks. Two-way repeated measures of ANOVA assessed time-group interactions and main effects, and paired -tests and one-way ANOVA were used post hoc with significance set at 0.05. The CES-D scores demonstrated significant interaction ( < 0.001), decreasing significantly in the BG and WG ( < 0.01) while rising in the CG ( < 0.05). Post hoc analysis revealed significantly lower depression levels in the BG compared to the CG ( < 0.01). Stress hormones epinephrine and cortisol showed a main effect of time ( < 0.05), with epinephrine increasing significantly in the BG ( < 0.05) and cortisol decreasing in the BG and WG ( < 0.05). An interaction effect emerged in hs-CRP levels ( < 0.05), while IgA and IgM displayed interaction effects ( < 0.05 and < 0.01, respectively), both significantly increasing in the BG ( < 0.05). In summary, regular exercise positively impacted depression, stress hormones, and immune functions in older women.
本研究探讨了一项为期12周的步行和芭蕾训练计划对65岁及以上女性抑郁水平(采用流调中心用抑郁量表)、应激激素(多巴胺、肾上腺素、去甲肾上腺素、皮质醇、血清素)、高敏C反应蛋白(hs-CRP)和免疫球蛋白(IgA、IgG、IgM)的影响。27名参与者被分为步行训练组(WG)、芭蕾训练组(BG)和对照组(CG),每组9人。训练课程持续50分钟,每周三次,强度每4周增加一次。采用双向重复测量方差分析评估时间-组间交互作用和主效应,并在事后使用配对检验和单因素方差分析,显著性水平设定为0.05。流调中心用抑郁量表评分显示出显著的交互作用(P<0.001),在芭蕾训练组和步行训练组中显著降低(P<0.01),而在对照组中升高(P<0.05)。事后分析显示,与对照组相比,芭蕾训练组的抑郁水平显著更低(P<0.01)。应激激素肾上腺素和皮质醇显示出时间主效应(P<0.05),其中芭蕾训练组的肾上腺素显著增加(P<0.05),而芭蕾训练组和步行训练组的皮质醇均降低(P<0.05)。高敏C反应蛋白水平出现了交互效应(P<0.05),而免疫球蛋白A和免疫球蛋白M显示出交互效应(分别为P<0.05和P<0.01),两者在芭蕾训练组中均显著增加(P<0.05)。总之,规律运动对老年女性的抑郁、应激激素和免疫功能产生了积极影响。