Rajpal Avichal, Pannu Ashok Kumar, Behera Ashish, Sharma Navneet, Hanumanthappa Mohan Kumar
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Indian J Crit Care Med. 2025 Feb;29(2):148-150. doi: 10.5005/jp-journals-10071-24896. Epub 2025 Jan 31.
Dengue viral infection (DVI) affects ~ 400 million people annually, with ~ 100 million cases causing clinical illness. Limited therapeutic options often lead patients to adopt alternative remedies. This study evaluates the prevalence and impact of such remedies on outcomes in patients admitted to a tertiary care emergency department.
A single-center, observational study was conducted from July 2022 to September 2023, including 170 patients aged >12 years with severe DVI or DVI with warning signs, as per the World Health Organization (WHO) criteria. The use of local remedies such as goat's milk, papaya leaves/extract, neem leaves, giloy juice, and alternative medicine was documented. Outcomes, including mortality and hospital stay duration, were compared between remedy users and non-users.
The mean age of participants was 36 years, with 60% males and 50% from rural areas. 35.29% used local remedies, with goat's milk (23.52%) and papaya leaves/extract (15.29%) being the most common. The median duration of remedy use was 2 days. Mortality was 6.67% in remedy users and 8.4% in non-users ( = 0.28). The median hospital stay was 4 days for both groups, with no significant outcome differences.
One-third of DVI patients used local remedies, with goat's milk being the most prevalent. However, no significant impact on mortality or hospital stay was observed.
Rajpal A, Pannu AK, Behera A, Sharma N, Hanumanthappa MK. Utilization of Local Remedies among Dengue Patients Admitted to the Emergency Department of a Tertiary Care Center: An Observational Study. Indian J Crit Care Med 2025;29(2):148-150.
登革病毒感染(DVI)每年影响约4亿人,其中约1亿例导致临床疾病。治疗选择有限常常导致患者采用替代疗法。本研究评估了此类疗法在三级医疗急诊科住院患者中的流行情况及其对预后的影响。
于2022年7月至2023年9月进行了一项单中心观察性研究,纳入170例年龄大于12岁、符合世界卫生组织(WHO)标准的重症DVI或有警示体征的DVI患者。记录了羊奶、番木瓜叶/提取物、印楝叶、匙羹藤汁等当地疗法以及替代药物的使用情况。比较了使用疗法者和未使用者的预后,包括死亡率和住院时间。
参与者的平均年龄为36岁,男性占60%,50%来自农村地区。35.29%的患者使用当地疗法,其中羊奶(23.52%)和番木瓜叶/提取物(15.29%)最为常见。使用疗法的中位持续时间为2天。使用疗法者的死亡率为6.67%,未使用者为8.4%(P = 0.28)。两组的中位住院时间均为4天,预后无显著差异。
三分之一的DVI患者使用当地疗法,其中羊奶最为普遍。然而,未观察到对死亡率或住院时间有显著影响。
Rajpal A, Pannu AK, Behera A, Sharma N, Hanumanthappa MK. 三级医疗中心急诊科收治的登革热患者使用当地疗法的情况:一项观察性研究。《印度重症医学杂志》2025;29(2):148 - 150。