对……中细菌感染的静止反应
Quiescent behavior in response to bacterial infection in .
作者信息
Moses Daniel, Needham Carly A, DeBardeleben Hilary
机构信息
Department of Biological Sciences, Duquesne University, Pittsburgh, Pennsylvania, United States.
Biology and Health Sciences, Commonwealth University - Bloomsburg.
出版信息
MicroPubl Biol. 2025 Mar 5;2025. doi: 10.17912/micropub.biology.001412. eCollection 2025.
Sickness behaviors serve an important role in recovery from infection. Using the WorMotel and a motivated displacement assay, we show that engages in quiescent behavior following infection with , a bacterial pathogen. This quiescence is increased with increasing severity of the infection. Furthermore, we show this behavior is distinct from stress-induced sleep due to a lack of feeding quiescence and regulation by sleep-inducing neurons.
疾病行为在感染恢复过程中起着重要作用。利用WorMotel和一种动机性位移测定法，我们发现感染细菌病原体后会进入静止行为。这种静止状态会随着感染严重程度的增加而增强。此外，我们发现这种行为与应激诱导的睡眠不同，因为它缺乏进食静止状态且不受诱导睡眠神经元的调节。
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